晚期前列腺癌耻骨上单切口双侧睾丸切除术

胡军全　朱圣煌　潘闰梅　黄绍明　李彤

【摘要】 目的：分析晚期前列腺癌恥骨上单切口双侧睾丸切除术的应用效果。方法：选取本院收治的晚期前列腺癌患者64例，根据治疗方法不同将其分为对照组（n=31）和观察组（n=33）。对照组行常规双侧睾丸切除术治疗，观察组行耻骨上单切口双侧睾丸切除术治疗。比较两组手术状况、住院时间、住院费用、手术疗效、并发症及治疗前后的生活质量评分。结果：观察组总有效率为96.97%，高于对照组的80.65%（P<0.05）；观察组术中出血量、手术时间分别为（22.74±10.51）mL、（12.37±2.81）min，均低于对照组的（59.68±18.47）mL、（37.24±8.65）min，比较差异均有统计学意义（P<0.05）；对照组阴囊血肿、切口感染发生率分别为12.90%、16.13%，而观察组均未出现这两种并发症，比较差异均有统计学意义（P<0.05）；治疗后，观察组的生活质量评分为（7.30±1.02）分，显著高于对照组的（5.84±0.92）分，比较差异有统计学意义（P<0.05）。结论：耻骨上单切口双侧睾丸切除术用于晚期前列腺癌患者治疗，可有效提升治疗总有效率，缩短手术时间，降低术中出血量，抑制阴囊血肿、切口感染等并发症的发生，提高患者生活质量，临床价值极高。

【关键词】 晚期前列腺癌； 耻骨上单切口； 双侧睾丸切除术

Effect of Bilateral Orchiectomy with Suprapubic Single Incision in Treatment of Advanced Prostate Cancer/HU Junquan，ZHU Shenghuang，PAN Runmei，et al.//Medical Innovation of China，2018，15（06）：046-049

【Abstract】 Objective：To analyze the effect of bilateral orchiectomy with suprapubic single incision in treatment of advanced prostate cancer.Method：A total of 64 patients with advanced prostate cancer who were treated in our hospital were selected，according to the difference of treatment methods，they were divided into control group（n=31） and observation group（n=33）.The control group was treated with routine bilateral testicle excision，and observation group was treated with bilateral orchiectomy with suprapubic single incision.The operation condition，hospitalization time，hospitalization cost，curative effect，complications and quality of life score before and after treatment between two groups were compared.Result：The total effective rate of observation group was 96.97%，which was higher than 80.65% of control group（P<0.05）.The intraoperative blood loss and operative time in observation group were（22.74±10.51）mL and （12.37±2.81）min respectively，which were lower than（59.68±18.47）mL and（37.24±8.65）min in control group，the differences were statistically significant（P<0.05）.The incidence of scrotal hematoma and incision infection in control group was 12.90% and 16.13% respectively，while there were no two kinds of complications in observation group，the differences were statistically significant（P<0.05）.After treatment，the quality of life score in observation group was（7.30±1.02）points，which was significantly higher than（5.84±0.92）points of control group，the difference was statistically significant（P<0.05）.Conclusion：Bilateral orchiectomy with suprapubic single incision for treatment of advanced prostate cancer patients，can effectively improve the treatment efficiency，shorten operation time，reduce intraoperative bleeding and inhibit scrotal hematoma，incision infection and other complications，improve the quality of life of patients，which is of high clinical value.