酉时中药烫熨治疗老年性骨质疏松症的疗效分析

2019-08-19 03:38夏一娇
中外医疗 2019年14期
关键词:骨质疏松症

夏一娇

[摘要] 目的 分析酉时中药烫熨治疗老年性骨质疏松症的疗效。 方法 便利选取2016年6月— 2018年8月在辽宁中医药大学附属医院骨K2科住院的100例老年性骨质疏松症患者。按随机数字表,将他们平均分为对照组与治疗组。对照组只给予钙尔奇 D3片及骨化三醇胶丸口服治疗,治疗组在对照组治疗的基础上于酉时行中药(熟地,细辛,白芍,杜仲,续断,金狗脊,牛膝)烫熨患部。观察两组患者骨密度值、相关生化指标、疼痛评分、疗效及功能改善情况。 结果 治疗组骨密度值[腰椎(0.84±0.05)g/m2,髋部(0.85±0.04)g/m2],明显高于对照组[腰椎骨密度(0.76±0.01)g/m2,髋部骨密度(0.78±0.03)g/m2(P<0.05),治疗组碱性磷酸酶指标下降(t=5.441,P<0.05),治疗组VAS 评分(2.25±0.64)分,显著低于对照组(5.32±0.85)分(t=8.364,P<0.05),Oswestry指数治疗组(60.21±5.74)分显著低于对照组(71.35±5.54)分(P<0.05)。 结论 酉时中药烫熨能有效增加骨密度、调节钙磷代谢,减轻骨痛,改善功能活动障碍。

[关键词] 骨质疏松症;酉时;中药烫熨

[中图分类号] R259          [文献标识码] A          [文章编号] 1674-0742(2019)05(b)-0150-04

[Abstract] Objective To analyze the efficacy of traditional Chinese medicine ironing in the treatment of senile osteoporosis. Methods From June 2016 to August 2018, Convenient select 100 cases of senile osteoporosis were admitted to the K2 department of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine. They were divided into a control group and a treatment group by random number table. In the control group, only Calcium D3 tablets and calcitriol capsules were given orally. The treatment group was treated with traditional Chinese medicine on the basis of the control group (rehmannia, asarum, white peony, eucommia ulmoides, continuation, golden dog ridge, achyranthes) ironing the affected area. The bone mineral density, related biochemical indicators, pain score, efficacy and functional improvement were observed in the two groups. Results The bone mineral density of the treatment group [lumbar vertebrae (0.84±0.05)g/m2, hip bone mineral density was (0.85±0.04)g/m2] was significantly higher than the control group [lumbar vertebrae density (0.76±0.01)g/m2, hip bone mineral density was (0.78±0.03)g/m2] (P<0.05), and the alkaline phosphatase index of the treatment group decreased (t=5.441, P<0.05). VAS score of the treatment group (2.25±0.64)points was significantly lower than the control group(5.32±0.85)points(t=8.364, P<0.05), and the Oswestry index treatment group (60.21±5.74)points was significantly lower than the control group (71.35±5.54)points (P<0.05). Conclusion Chinese herbal medicine can effectively increase bone density, regulate calcium and phosphorus metabolism, reduce bone pain and improve functional activity disorder.

[Key words] Osteoporosis; Sputum; Chinese medicine ironing

我國是人口老龄化大国,以髋关节为例,每年由于重度骨质疏松症导致髋关节骨折的患者有近20万人以上,骨质疏松症已成为危害老年人生存质量的重症之一[1-3],该病主要的临床表现为广泛性的骨痛、乏力、稍有不慎即可发生脆性骨折。该文旨在分析2016年6月— 2018年8月在中医药理论指导下酉时中药烫熨对100例老年性骨质疏松症患者的治疗作用。报道如下。

該研究两组患者治疗后骨密度都显著增加。治疗组[腰椎骨密度0.84±0.05)g/m2,髋部骨密度(0.85±0.04g/m2],明显高于对照组[腰椎骨密度(0.76±0.01g/m2,髋部骨密度(0.78±0.03)g/m2,碱性磷酸酶均有所降低。治疗组碱性磷酸酶(53.21±4.1)U/L]显著降低,差异有统计学意义(P<0.05)。两组患者血肌酐、血钙都有所下降,治疗组血肌酐、血钙差异无统计学意义(P>0.05),说明血钙降低则碱性磷酸酶降低,碱性磷酸酶作为骨转换生化标记物,可以显著抑制破骨细胞的骨吸收。疼痛方面,治疗组VAS 评分(2.25±0.64)分显著低于对照组(5.32±0.85)分(P<0.05),Oswestry指数治疗组(60.21±5.74分)显著低于对照组(71.35±5.54)分(P<0.05)。有研究对78例老年骨质疏松患者采用中药薰蒸结合密盖息肌内注射,取得了94.9%的总有效率,较该研究低1.1%。相关学者等对46例原发性骨质疏松患者采用中药熏洗治疗,取得了87%的总有效率,VAS评分改善为(1.2±0.4)分。总有效率较该研究低9%,VAS评分较该研究高了大约1分。说明该方法能明显减轻患者疼痛,改善功能障碍。综上,酉时中药烫熨治疗老年性骨质疏松症疗效肯定,且操作安全,经济实惠,值得临床推广使用。

[参考文献]

[1]  Wang L,Hu YQ,Zhao ZJ,et al.Screening and validation of serum protein biomarkers for early postmenopausal osteoporosis diagnosis[J].Mol Med Rep,2017,16(6):8427-8433.

[2]  García - Gomáriz C,Blasco JM,Macián - Romero C,et al.Effect of 2 years of endurance and high - impact training on preventing osteoporosis in postmenopausal women:randomized clinical trial[J].Menopause,2018,25(3): 301-306.

[3]  Moradi S,Khorrami - Nezhad L,Maghbooli Z,et al.Vitamin D receptor gene variation,dietary intake and bone mineral density in obese women: a cross sectional study[J].J Nutr Sci

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