左氧氟沙星与桑白皮苇茎汤治疗社区获得性呼吸道感染疗效比较

莫剑良 陈敬欢 罗婉嫦

[摘要] 目的 探讨左氧氟沙星与桑白皮苇茎汤治疗社区获得性呼吸道感染的临床对比疗效。 方法 收集2008年12月～2011年12月在本社区卫生服务中心就诊的社区获得性呼吸道感染患者共40例，根据先后顺序平分为治疗组与对照组各20例，治疗组采用左氧氟沙星静脉给药方法，对照组给予桑白皮苇茎汤口服治疗。 结果 治疗组的总有效率（显效+有效/总例数）为95.0%，对照组总有效率为75.0%，治疗组的临床疗效明显好于对照组（P < 0.05）。同时两组都无明显不良反应情况发生（P > 0.05）。 结论 左氧氟沙星注射液治疗社区获得性呼吸道感染有更好的临床效果，值得推广应用。

[关键词] 社区获得性呼吸道感染；左氧氟沙星；桑白皮苇茎汤；疗效比较

[中图分类号] R974[文献标识码] A[文章编号] 1674-4721（2012）07（c）-0115-02

Comparison on therapeutic effect of Levofloxacin and Morus alba reed stems soup in the treatment of community-acquired respiratory infections

MO Jianliang CHEN Jinghuan LUO Wanchang

Community Health Service Center of Qiaotou Town in Dongguan City, Guangdong Province, Dongguan 523528, China

[Abstract] Objective To investigate the clinical comparative efficacy of Levofloxacin and Morus alba reed stems soup in the treatment of community-acquired respiratory infections. Methods Forty patients of community-acquired respiratory infections for treatment in our community from December 2008 to December 2011 were collected, and divided into two groups by the order in hospital, the treatment group and control group, 20 cases in each group, the treatment group was given Levofloxacin with the administration method of intravenous, the control group was given Morus alba reed stems soup by oral. Results The total efficiency rate of the treatment group was 95.0%, of the control group was 75.0%, the clinical efficacy rate of the treatment group was significantly better than that of the control group (P < 0.05). Both groups had no obvious adverse reaction happened (P > 0.05). Conclusion Levofloxacin injection has a better clinical effect for the treatment of community-acquired respiratory infections, which is worthy of widely application.

[Key words] Community-acquired respiratory infections; Levofloxacin; Morus alba reed stems soup; Effect comparison

社區获得性呼吸道感染是严重危害人体生存及健康的主要疾病，选择敏感的抗生素治疗，从而有效地控制感染至关重要[1]。引起社区获得性呼吸道感染的病原体主要有细菌、真菌、衣原体、支原体、病毒等微生物，其中以细菌性炎症最为常见。近年来社区获得性呼吸道感染的病原体出现了一些变化或变迁，肺炎链球菌的比例有所下降，革兰阴性杆菌所占比例较前增加。及时正确的经验性治疗是挽救生命的关键，而提高社区获得性呼吸道感染病原菌的分离率，连续对社区获得性呼吸道感染病原菌的耐药性监测资料是临床医生正确选择抗菌药物的重要依据[2-3]。当前临床试验研究表明左氧氟沙星在骨骼、肺、皮肤、泌尿、生殖和中枢等组织系统感染的治疗上效果显著，由于左氧氟沙星所表现出来的优点，目前在呼吸系统感染的治疗中广泛应用。……