速度向量成像技术评价高脂血症颈总动脉管壁运动特性及力学的临床价值

范国裕+齐继连+彭云蓉+黎明

[摘要] 目的 探讨速度向量成像技术（VVI）评价高脂血症患者颈总动脉管壁运动特性及力学的临床价值。 方法 选取2011年10月～2012年10月在本院治疗的高脂血症患者32例，设为观察组，另选择同期健康志愿者31例，设为对照组。采用VVI技术对两组患者进行检测分析，并比较两组患者二维图像上前壁、内侧壁、后壁及外侧壁的收缩期Vmax、Smax及SRmax。 结果 观察组的IMT明显厚于对照组，Ds明显短于对照组，PSV明显慢于对照组，差异有统计学意义（P＜0.05）。观察组前壁、内侧壁、后壁及外侧壁的Vmax、Smax及SRmax均显著高于对照组，差异有统计学意义（P＜0.05）。 结论 VVI技术能较好地评价颈总动脉管壁运动特征，可显示颈总动脉管壁的弹性特点，从而较好地评价高脂血症颈总动脉管壁运动特性及力学。

[关键词] 速度向量成像；高脂血症；颈总动脉壁；管壁运动特性

[中图分类号] R589.2[文献标识码] A[文章编号] 1674-4721（2014）04（c）-0026-03

Clinical value of velocity vector imaging in the evaluation of motion characteristic of carotid artery wall and mechanical with hyperlipidemia

FAN Guo-yu QI Ji-lian PENG Yun-rong LI Ming▲

Department of Ultrasound,People′s Hospital of Longgang District in Shenzhen City,Shenzhen 518172,China

[Abstract] Objective To investigate clinical value of velocity vector imaging in the evaluation of motion characteristic of carotid artery wall and mechanical with hyperlipidemia. Methods 32 cases of patients with hyperlipidemia were selected from October 2011 to October 2012 in our hospital as observation group,another 31 healthy volunteers were selected as control group.VVI technique was used in patients of two groups,the peak systolic velocity,strain and strain rate of forward wall,medial wall,posterior wall and lateral wall in two-dimensional image in two groups was compared respectively. Results IMT of observation group was significantly thicker than that of control group,Ds of observation group was significantly shorter than that of control group,PSV of observation group was significantly slower than that of control group,with statistical difference(P＜0.05).Vmax,Smax and SRmax of the anterior wall,posterior wall,the medial wall and lateral wall in observation group was significantly higher than that in control group,with statistical difference(P＜0.05). Conclusion Common carotid artery all motion characteristic can better evaluate VVI technology,can display the carotid artery wall elasticity characteristic,so as to can better evaluate hyperlipidemia carotid arterial wall motion characteristic and mechanical.

[Key words] Velocity vector imaging;Hyperlipidemia;Carotid artery wall;Wall motion characteristic

近年来，高脂血症是冠心病发病的重要危险因素之一，已受到临床的高度重视[1-2]。有报道提出高脂血症患者颈总动脉壁粥样硬化斑块改变，可导致患者动脉内膜运动特征及形变能力随之发生改变[3-4]。高脂血症患者颈总动脉壁粥样硬化斑块改变与正常人相比差异较为明显，可以用来作为对照进行临床分析。本文主要通过速度向量成像技术（velocity vector imaging，VVI）评价颈总动脉管壁运动特性及力学的临床价值。

1 资料与方法

1.1 一般资料

选取2011年10月～2012年10月在本院治疗的高脂血症患者32例，设为观察组，男18例，女14例，年龄44～71岁，平均（49.8±10.4）岁，纳入标准：①血清总胆固醇（total cholesterol，TC）≥5.74 mmo/L；……