中西医结合治疗小儿消化性溃疡的临床效果观察

杨武萍

[摘要] 目的 探讨中西医结合治疗小儿消化性溃疡的临床效果。 方法 选取85例消化性溃疡患儿作为研究对象，分为对照组42例与研究组43例。对照组给予常规西药治疗，研究组在对照组的基础上给予中药汤剂治疗。 结果 研究组的总有效率为95.35%，明显高于对照组的76.19%（P<0.05）；研究组的愈合率、Hp根除率均明显高于对照组（P<0.05）；研究组的不良反应发生率为11.63%，对照组为11.90%，两组比较，差异无统计学意义（P>0.05）。 结论 中西医结合治疗小儿消化性溃疡能有效提高愈合率与Hp根除率，效果显著，值得推广。

[关键词] 消化性溃疡；中西医结合；雷贝拉唑

[中图分类号] R725.7 [文献标识码] A [文章编号] 1674-4721（2014）09（a）-0131-03

Clinical observation effect of integrated traditional Chinese and western medicine treating peptic in children

YANG Wu-ping

Department of Pediatrics，Central Hospital of Xinyu Iron and Steel Copany of Xinyu City in Jiangxi Province，Xinyu 338000，China

[Abstract] Objective To explore the clinical effect of integrated traditional Chinese and western medicine treating peptic in children. Methods 85 children with peptic ulcer were selected as research subjects and they were divided into the control group （n=42） and the research group （n=43）.The control group received the treatment of regular western medicine，and the research group received decoction of traditional Chinese medicine on the basis of the control group. Results The total effective rate in the research group （95.35%） was significantly higher than that of the control group （76.19%） （P<0.05）；recovery rate and Hp eradication rate in the research group were significantly higher than those in the control group （P<0.05）；incidence rate of adverse effect was 11.63% in the research group and 11.90% in the control group，and the difference was not statistically significant （P>0.05）. Conclusion Integrated traditional Chinese and western medicine in the treatment of peptic ulcer for children helps effectively improve recovery rate and Hp eradication rate，which has a significant curative effect and worthy of clinical promotion.

[Key words] Peptic ulcer；Integrated traditional Chinese and western medicine；Rabeprazole

消化性溃疡是一种发生在胃与十二指肠的消化系统疾病，多伴有出血，常见于儿童。该病具有起病急、变化快以及病情复杂等特点[1]。为了探讨中西医结合治疗小儿消化性溃疡的临床效果，本院以85例消化性溃疡患儿作为研究对象进行分析。

1 资料与方法

1.1 一般资料

收集本院于2011年2月～2014年2月收治85例消化性溃疡患儿的临床资料。将患儿分为两组，研究组共43例，男27例，女性16例，年龄1～12岁，平均（6.8±1.4）岁；对照组共42例，男23例，女19例，年龄2～11岁，平均（6.6±1.2）岁。排除合并严重的心、肝、肾功能不全，胃癌，合并溃疡出血穿孔等疾病的患儿。两组患儿的性别、年龄等一般资料差异无统计学意义（P>0.05），具有可比性。

1.2方法

对照组给予常规西药治疗，即口服雷贝拉唑钠肠溶片（国药准字H20031292，上海信谊药厂有限公司，规格10 mg）20 mg /次，2 次/d+阿莫西林胶囊（国药准字H20056323，广东彼迪药业有限公司，规格0.25 g）1.0 g/次，2次/d+呋喃唑酮片（国药准字H34020811，芜湖中加生物制药股份有限公司，规格0.1 g）0.2 g /次，2次/d治疗，疗程为7 d。研究组在西药的基础上加用中药汤剂治疗，主药方包括黄芪、瓦楞子各30 g、海螵蛸20 g，茯苓、党参、丹参、白芨、白芍、大黄各15 g，三七、仙鹤草、红花、莪术、甘草各10 g。1……