雷雅男
阴道镜在宫颈癌筛查中的应用评估
雷雅男
【摘要】目的 探讨阴道镜在宫颈癌筛查中的应用价值。方法 收集2013年5月~2014年6月我院妇科门诊就诊,接受TCT、阴道镜及高危HPV检查的患者,共计268例,年龄19~54岁,平均年龄(39.6±16.7)岁。对比:(1)TCT、阴道镜及高危HPV检测阳性检查例数及敏感度。(2)TCT、阴道镜及高危HPV检测与金标准病理结果的诊断对比。结果(1)TCT、阴道镜及高危HPV检测阳性检查例数及敏感度结果比较有差异(P<0.05),以高危HPV敏感性最高。(2)与金标准病理结果对比,TCT、阴道镜及高危HPV检测对诊断CINI、CINII、CINIII、宫颈癌的阳性率结果比较有差异(P<0.05)。结论本次研究认为TCT、阴道镜和高危HPV检测相互结合后可以提高宫颈癌的早期诊断阳性率。
【关键词】阴道镜;宫颈癌;筛查
Objective To investigate the value of the application of colposcope in the screening of cervical cancer. Methods We collected patients in our hospital from May 2013 to June 2014,and received TCT,and high risk HPV,268 patients,aged 19~54 years old,average age(39.6±16.7)years old. Contrast(1)TCT,and high risk HPV test positive test cases and sensitivity. (2)TCT,and high risk HPV test and the diagnosis of gold standard pathological findings. Results (1)TCT,and high risk HPV test positive for the number of cases and the sensitivity of the results were different(P<0.05),highest risk of HPV. (2)compared with the gold standard pathology,TCT,CIN and HPV were detected by I,CIN,II,III and CIN,and the positive rate of cervical cancer was different(P<0.05). Conclusion This study suggests that the combination of TCT,HPV and high risk detection can improve the positive rate of early diagnosis of cervical cancer.
【Key words】Cervical,Cancer,Screening
宫颈病变为当今女性十分多见的病种,而宫颈癌中预后最差。宫颈癌是常见的女性生殖道恶性肿瘤之一,位居于女性第二位恶性肿瘤,但是宫颈癌发展缓慢,若早期进行筛查,发现癌前病变,可以防患于未然[1]。宫颈暴露方便,能够直视下查看、取材,如果女性能够定期普查,就可较早发现其早期病变。因此选择敏感性好、特异性强的检查工具尤为重要。有学者指出阴道镜对于评估宫颈的病变有效果。阴道镜检查可以了解病变区血管情况,通过具有放大技术可动态反复检查宫颈病灶,并快速判断病灶的良恶性,是一种操作方便的诊断方法。因此本次研究中我们选择临床中常用的TCT、阴道镜及高危HPV检测作对比,拟评价阴道镜在宫颈癌筛查中的价值。……