依达拉奉联合奥扎格雷治疗急性脑梗死的疗效分析

2015-08-29 06:24:37张坤
中外医疗 2015年7期

张坤

[摘要] 目的 研究依达拉奉联合奥扎格雷治疗急性脑梗死的疗效。 方法 选取该院2012年1月—2014年10月间诊治的急性脑梗死患者120例,将其随机分为观察组和对照组各60例,对观察组患者采用依达拉奉联合奥扎格雷治疗,对对照组患者进行单纯的依达拉奉治疗,对比观察两组患者的临床治疗效果及C反应蛋白水平。 结果 观察组患者中,痊愈的患者为27例,显效的患者为21例,有效的患者为7例,无效的患者为5例,总有效率为91.67%,对照组患者中,痊愈的患者为11例,显效的患者为26例,有效的患者为12例,无效的患者为11例,总有效率为81.67%,观察组明显高于对照组,两组对比,差异有统计学意义(P<0.05);在C反应蛋白水平方面,观察组患者在治疗后为(7.06±1.43) mg/L,对照组患者在治疗后为(4.06±1.71) mg/L,观察组的下降水平明显高于对照组患者的水平,两组差异有统计学意义(P<0.05)。 结论 采用依达拉奉联合奥扎格雷治疗急性脑梗死不仅可以提高临床治疗效果,而且能够大大降低C反应蛋白水平,值得临床推广使用。

[关键词] 依达拉奉;奥扎格雷;急性脑梗死;C反应蛋白水平

[中图分类号] R74 [文献标识码] A [文章编号] 1674-0742(2015)03(a)-0136-03

Analysis of therapeutic effect of edaravone combined with ozagrel in treatment of acute cerebral infarction.

ZHANG Kun

Department of Neurology in Dashiqiao Central Hospital,Yingkou Liaoning province,115100 China

[Abstract] Objective To study the therapeutic effect of edaravone combined with ozagrel in treatment of acute cerebral infarction. Methods Selected 120 patients with acute cerebral infarction in our hospital and randomly divided into observation group and control group with 60 cases in each group.The observation group were treated by edaravone combined with ozagrel treatment,the control group patients were given edaravone treatment alone. Compared two groups of clinical therapeutic effect and the level of C-reactive protein. Results The total effective rate of observation group was 91.67%,the control group the total effective rate was 81.67%,the observation group was significantly higher than that in the control group,with significant difference (P < 0.05); C reaction protein of the observation group after treatment was (7.06±1.43),which of the control group was (4.06±1.71),the decreased level of the observation group was significantly higher than the control group levels,with statistically significant difference (P < 0.05). Conclusion The use of edaravone combined with ozagrel in treating acute cerebral infarction can not only improve the clinical treatment effect,but also can greatly reduce the level of C reactive protein,is worthy of clinical use.

[Key words] Edaravone; Ozagrel; Acute cerebral infarction; C reactive protein

在临床中,由各种原因引发的脑部血液供应不足而造成的脑组织缺血及缺氧性坏死,从而出现相应的神经功能缺损症状被称之为脑梗死。其中对人们生命健康威胁最大的是急性脑梗死,其特征在于发病急且病情发展迅速,致残率高[1]。该研究选取该院2012年1月—2014年10月间收治的急性脑梗死患者120例作为对象,研究依达拉奉联合奥扎格雷治疗急性脑梗死的疗效,现报道如下。

1 资料与方法

1.1 一般资料

选取该院收治的急性脑梗死患者120例,所有患者均有典型的病史和明确的神经系统定位体征,瘫痪肢体肌力为0~3级,经过头颅CT检查后均排除脑出血。将其随机平均分为观察组和对照组,其中观察组包括男性患者39例,女性患者21例;……

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