风眩宁方治疗后循环缺血性眩晕

风眩宁方治疗后循环缺血性眩晕

王长德，钟萍，冯蓓蕾，陈婡，魏然，周学春，童舒雯

(上海中医药大学附属上海市中西医结合医院，上海 200082)

摘要：目的观察风眩宁方治疗后循环缺血性眩晕(风痰上扰型)的临床疗效，并以经颅多普勒超声(TCD)和彩色多普勒超声(CDFI)做为疗效评估的手段，探讨其作用机制。方法选取后循环缺血性眩晕患者100例，随机分为治疗组50例和对照组50例，2组均给予抗血小板聚集、控制血压、降糖、调脂、镇静等基础治疗。治疗组给予中药风眩宁方治疗，对照组给予盐酸氟桂利嗪胶囊治疗。2组疗程均为12 d，观察2组患者眩晕程度改善情况及治疗前后TCD双侧椎动脉(VA)和基底动脉(BA)的平均血流速度(Vm)，CDFI最大血流速度(Vmax),阻力指数(RI)。结果治疗组总有效率92.0%，对照组总有效率76.0%，2组疗效比较有统计学意义(P<0．05)。2组治疗后平均血流速度及最大血流速度均有明显改善，与治疗前比较差异均有统计学意义(P<0．05)，治疗后2组比较有统计学意义(P<0．05)。2组阻力指数与治疗前比较差异有统计学意义(P<0．05)，治疗后2组比较差异无统计学意义(P>0．05)。结论风眩宁方能有效改善后循环缺血性眩晕患者的眩晕症状，并能改善后循环缺血患者椎-基底动脉血流速度。

关键词：后循环缺血性眩晕；风眩宁方；风痰上扰；熄风化痰；活血通络；健脾利湿

DOI:10.13463/j.cnki.jlzyy.2015.11.009

中图分类号：R255.3文献标志码： A

基金项目：上海市虹口区医学重点专科建设项目(虹卫20151003)；上海市虹口区卫生局资助项目(虹卫13-03)。

作者简介：王长德(1968-)，男，硕士研究生，主任医师，主要从事中医脑病的临床及基础研究。

收稿日期:(责任编辑：张晔2015-07-28)

Subsidence wind vertigo prescription treatment of circulating cerebral ischemic vertigo

WANG Changde, ZHONG Ping, FENG Beilei, CHEN Lai, WEI Ran, ZHOU Xuechun, TONG Shuwen

(Shanghai TCM-Integrated Hospital Affiliated to Shanghai University of TCM，Shanghai 200082, China)

Abstract：ObjectiveTo study the clinical treatment of Subsidence wind vertigo prescription circulating cerebral ischemic vertigo (Disturbance of wind phlegm type), and to evaluate efficacy with means of transcranial Doppler (TCD) and Color Doppler Flow Imaging (CDFI)to explore its mechanism of action. MethodsOne hundred patients with posterior circulation ischemia (PCI) were randomly divided into two groups, the treatment group (50 cases) treated with Chinese traditional medicin e-Subsidence wind vertigo prescription and the control group(50 cases) treated with Flunarizine capsules , which were both given 12 days conventional treatment, such as antiplatelet aggregative, blood pressure control, lipid-adjusting, sedation and so on. Observe the improvement of the both groups of patients with vertigo, and compare TCD indicated the average blood flow rate (Vm) of bilateral Vertebral artery (VA) and Basilar artery (BA), CDFI indicated the maximum blood rate (Vmax), resistance index (RI) before and after treatment. ResultsThe clinical therapeutic effect: total efficiency of 92.0%; the control group, the total efficiency of 76.0%. Two groups has statistical significance (P<0.05). Compared Resistance index of both groups before treatment has statistical significance (P<0.05), while after treatment has no statistical significance (P>0.05). ConclusionSubsidence wind vertigo prescription can effectively improve the posterior circulation ischemic vertigo in patients with clinical symptoms, and the blood flow rate of vertebral artery and basilar artery, suggesting that the efficacy of Subsidence wind vertigo prescription.

Keywords：posterior circulation cerebral ischemia; subsidence wind vertigo prescription; disturbance of wind phlegm; extinguish wind and removing phlegm; promoting blood circulation to remove meridian obstruction; invigorate spleen to damp elimination

后循环缺血性眩晕是中老年常见多发病，占中老年人各种眩晕的60%以上[1]。随着人们生活水平的不断提高，人口老龄化的趋势越来越明显，其发病率也呈逐渐上升的趋势。……