舒肝解郁胶囊治疗对脑卒中后抑郁患者认知功能和睡眠质量的影响

马文强

舒肝解郁胶囊治疗
对脑卒中后抑郁患者认知功能和睡眠质量的影响

马文强

目的 探讨舒肝解郁胶囊治疗对脑卒中后抑郁患者认知功能和睡眠质量的影响。方法 选择2014年1月～2015年12月我院治疗的脑卒中后抑郁患者60例为研究对象。按照入院单双号分为研究组30例和对照组30例。对照组给予常规治疗，研究组在常规治疗基础上给予舒肝解郁胶囊治疗。比较两组认知功能障碍发生率睡眠质量。结果 研究组总的认知障碍发生率低于对照组，差异有统计学意义（P＜0.05）。两组治疗后睡眠质量评分均低于治疗前，差异有统计学意义（P＜0.05）；治疗后，研究组睡眠质量评分优于对照组，差异有统计学意义（P＜0.05）。结论 舒肝解郁胶囊能改善脑卒中后抑郁患者抑郁状态，改善患者认知功能障碍，提高患者生活质量，改善患者睡眠质量。

舒肝解郁胶囊；脑卒中；抑郁；认知功能；生活质量；睡眠质量

【Abstract】

Objective To discuss the influence of Shuganjieyu capsules on cognitive function and sleep quality in the treatment of depression after stroke. Methods 60 cases with depression after stroke in our hospital from January 2014 to December 2015 were selected. All cases were divided into study group and control group according to admission sequence，each group of 30 cases. The control group was given routine treatment，and the study group was given Shuganjieyu capsules treatment on the basis of routine treatment. Incidence of cognitive dysfunction and sleep quality after treatment of two groups were compared. Results The incidence of cognitive impairment in the study group was significantly lower than that in the control group，and the difference was statistically significant（P＜0.05）. After treatment，two groups after treatment sleep quality scores were lower than before treatment，the difference was statistically significant（P＜0.05）. The sleep quality score of the study group was significantly better than that of the control group，and the difference was statistically significant（P＜0.05）. Conclusion Shuganjieyu capsules for depression after stroke can significantly improve post-stroke depression and improve the cognitive impairment，the quality of life of patients and improve the quality of sleep.

【Key words】Shuganjieyu capsule，Stroke，Depression，Cognitive function，Quality of life，Quality of sleep

抑郁是脑卒中后常见的并发症之一，影响患者的认知功能、神经功能、睡眠质量、生活质量等，影响患者预后。舒肝解郁胶囊是一种重要复合制剂，具有抗抑郁的作用［1-2］。我们采用舒肝解郁胶囊治疗脑卒中后抑郁并发症，取得了较好的效果。现将结果报道如下。

1　资料与方法

1.1一般资料

选择2014年1月～2015年12月我院治疗的脑卒中后抑郁患者60例为研究对象。按照入院单双号分为研究组30例和对照组30例。纳入标准：脑卒中诊断明确，经影像学证实；符合抑郁症诊断标准；排除既往有精神病病史、神经病病史，排除不愿意参加研究的患者。……