邓亨平
【摘要】 目的:探讨QT间期(QTc)与急性ST抬高型心肌梗死患者梗死部位、心律失常类型及预后的关系。方法:选择430例急性ST抬高型心肌梗死患者作为研究对象,分析患者QTc、QRS宽度及左室射血分数(LVEF)与病情的关系。结果:随访1年,发生心血管不良事件患者与未发生心血管不良事件者比较,QTc、QRS宽度均显著延长,LVEF显著下降(P<0.05)。QTc延长组患者高侧壁、前壁心肌梗死发生率高于QTc正常组(P<0.05);QTc缩短组患者缓慢心律失常发生率显著高于QTc正常组(P<0.05)。QTc异常、QRS宽度延长及LVEF均为患者发生心血管不良事件的风险因素。结论:QTc与急性ST抬高型心肌梗死患者梗死部位及心律失常类型相关,QTc异常为患者预后不良的风险因素。
【关键词】 心肌梗死; QT间期; 预后
中图分类号 R542.22 文献标识码 A 文章编号 1674-6805(2016)6-0006-02
The Relationship of QTc with Location of Infarction,Types of Arrhythmia and Prognosis of the Patients with Acute ST-Elevation Myocardial Infarction/DENG Heng-ping.//Chinese and Foreign Medical Research,2016,14(6):6-7
【Abstract】 Objective:To explore the relationship of QTc with location of infarction,types of arrhythmia and prognosis of the patients with acute ST elevation myocardial infarction.Method:430 patients with acute ST-elevation myocardial infarction were selected as the research objects,the relationships of QTc,QRS duration and LVEF with disease condition were analyzed.Result:Follow up for 1 year,compared with the no adverse cardiovascular events,the QTc and QRS duration were greatly prolonged and LVED decreased of the patients with adverse cardiovascular events (P<0.05).The incidence of high side wall and anterior wall myocardial infarction of the QTc extension group was higher than that in the QTc normal group (P<0.05).Slow arrhythmia incidence rate of the QTc shortened group was higher than that in the QTc normal group (P<0.05).QTc abnormalities, QRS width extension and LVEF were all risk factors for adverse cardiovascular events.Conclusion:QTc is closely related with infarct location and the arrhythmia type,abnormal QTc is the risk factor for bad prognosis.
【Key words】 Myocardial infarction; QTc; Prognosis
First-authors address:The Central Hospital of Bazhong,Bazhong 636000,China
doi:10.14033/j.cnki.cfmr.2016.6.003
急性心肌梗死是由于心肌出現持续严重的缺血引起部分心肌发生坏死,患者出现急性循环功能障碍的临床表现[1]。急性心肌梗死病死率高,病情进展快,经皮冠状动脉介入术(PCI)及溶栓治疗显著降低了急性心肌梗死患者病死率[2]。急性心肌梗死患者临床常出现恶性心律失常,严重威胁患者生命。心电图在急性心肌梗死及心律失常的诊断和疗效评价中发挥重要作用,是一种简便易行的无创性指标。心电图QT间期是中层心肌细胞激动时间的反应,T波宽度表示心室复极时限。本研究将探讨QT间期(QTc)与急性ST抬高型心肌梗死患者梗死部位、心律失常类型及预后的关系,现报道如下。
1 资料与方法
1.1 一般资料
选取2012年8月-2014年6月笔者所在医院诊治的430例急性ST抬高型心肌梗死患者,男230例,女200例,年龄38~72岁,
平均58.6岁,均接受溶栓治疗,且均符合急性ST段抬高型心肌梗死诊断标准,其中肢体导联抬高超过0.1 mV,胸前导联超过0.2 mV,患者心电图支持急性心肌梗死的动态演变过程;心肌酶谱符合急性心肌梗死特点。……