湛江地区骨质疏松患者并发肿瘤疾病情况调查

王朝军，陈广谋，黄成硕，孔俊超，刘怀毫，蔡家尚，曾荣，魏波

广东医科大学附属医院骨科，广东湛江524001

湛江地区骨质疏松患者并发肿瘤疾病情况调查

王朝军，陈广谋，黄成硕，孔俊超，刘怀毫，蔡家尚，曾荣，魏波

广东医科大学附属医院骨科，广东湛江524001

目的对湛江地区骨质疏松患者进行初步调查分析，了解分析该地区骨质疏松患者并发肿瘤情况。方法随机选取50岁以上2011年1月1日—2016年1月1日期间在广东医科大学附属医院骨科治疗的骨质疏松患者194例进行统计分析，内容包括一般情况调查、初步的医学检查、静脉血检测及骨密度检测。194例骨质疏松患者中，根据有无肿瘤分为肿瘤组与非肿瘤组，肿瘤组又分为运动系统肿瘤，神经系统肿瘤，心血管系统肿瘤和呼吸系统肿瘤。结果骨质疏松患者中非肿瘤组和各个类型的肿瘤组在年龄、身高、体重、腰椎骨密度、血清磷和血清碱性磷酸酶上的差异均无统计学意义（P＞0.05）。运动系统肿瘤组的股骨骨密度和血清钙小于非肿瘤组且差异具有统计学意义（P＜0.05）。结论运动系统肿瘤患者可能是累及患者活动功能造成活动减小，可能影响钙的吸收和流失的平衡，从而影响骨密度值。

骨质疏松；肿瘤；血清钙

［Abstract］Objective To know and analyze the conditions of patients with osteoporosis combined with tumor disease in Zhanjiang region by carrying out the initial survey of them.Methods 194 cases of patients with osteoporosis aged above 50 years old treated in the department of orthopaedics in the Affiliated Hospital of Guangdong Medical University from January 1，2011 to January 1，2016 were randomly selected for statistical analysis，and the contents included the general condition survey，initial medical examination，venous blood detection and bone minering density detection，and all patients selected were divided into the tumor group and non-tumor group according to whether there were tumors or not，and the tumor group were divided into the motor system tumor，nervous system tumor，cardiovascular system tumor and respiratory system tumor. Results The differences in the age，height，weight，lumbar bone mineral density，serum phosphate and serum alkaline phosphatase between the non-tumor group and the tumor groups of various types had no statistical significance，P＞0.05，the bone mineral density and calcium serum in the motor system tumor group were less than those in the non-tumor group and the differences had statistical significance，P＜0.05.Conclusion The patients with motor system tumor may involve the physical function causing the motion decreases，which may affect the calcium absorption and loss balance thus affecting the bone density value.

［Key words］Osteoporosis；Tumor；Serum calcium

骨质疏松症是以骨量低下和骨微结构损坏，致使骨的脆性增加，容易发生骨折为特征的全身性的骨病，骨质疏松症也是退化性疾病。腰背疼和病理性骨折是骨质疏松症的临床表现，主要发生在中老年人，尤其是绝经后妇女。……