完善绿色通道及溶栓流程对提高急性缺血性脑卒中静脉溶栓率的应用评价

2017-03-28 15:32:37陈晓能孔令恩蔡春生
中国实用医药 2017年1期

陈晓能+孔令恩+蔡春生

【摘要】 目的 探索完善绿色通道及溶栓流程对提高急性缺血性脑卒中患者静脉溶栓率的效果。方法 2016年1~6月收治的35例急性缺血性脑卒中患者作为对照组, 2016年7~10月收治的41例急性缺血性脑卒中患者为观察组。对照组采用常规绿色通道及溶栓流程, 观察组采用完善的綠色通道及溶栓流程。对比分析两组患者的静脉溶栓率、就诊到溶栓治疗时间(DNT)、美国国立卫生研究院卒中量表(NIHSS)评分。结果 观察组的静脉溶栓率为87.80%, 高于对照组65.71%, 差异具有统计学意义 (P<0.05)。观察组静脉溶栓患者DNT为(67.0±8.4)min, 短于对照组的(94.5±10.2)min, 差异具有统计学意义(P<0.05)。入院时两组患者的NIHSS评分对比, 差异无统计学意义(t=0.324, P>0.05);溶栓后2、7 d, 观察组患者的NIHSS评分均低于对照组, 差异具有统计学意义 (t=2.765、5.790, P<0.05)。结论 完善针对急性缺血性脑卒中患者的绿色通道和溶栓流程有助于把握溶栓治疗的时间, 缩短DNT, 挽救生命, 早期行静脉溶栓治疗可促进患者神经功能的恢复, 提高患者生存质量。医院需结合实际情况不断完善绿色通道及溶栓流程, 挽救生命。

【关键词】 绿色通道;溶栓流程;急性缺血性脑卒中;静脉溶栓率;溶栓时间

DOI:10.14163/j.cnki.11-5547/r.2017.01.091

Application evaluation on perfection of green channel and thrombolytic process for increasing intravenous thrombolysis rate in acute cerebral ischemic stroke CHEN Xiao-neng, KONG Ling-en, CAI Chun-sheng. Huizhou City Boluo County Centers for Disease Control and Prevention, Huizhou 516001, China

【Abstract】 Objective To explore effect of perfection of green channel and thrombolytic process for increasing intravenous thrombolysis rate in acute cerebral ischemic stroke. Methods There were 35 acute cerebral ischemic stroke patients received from January to June 2016 as control group, and 41 acute cerebral ischemic stroke patients received from July to October 2016 as observation group. The control group received conventional green channel and thrombolytic process, and the observation group received perfect green channel and thrombolytic process. Comparison and analysis were made on intravenous thrombolysis rate, door-to-needle time (DNT) and national institute of health stroke scale (NIHSS) score in two groups. Results The observation group had higher intravenous thrombolysis rate as 87.80%, than 65.71% in the control group, and the difference had statistical significance (P<0.05). The observation group had shorter DNT as (67.0±8.4)min than (94.5±10.2)min

in the control group, and the difference had statistical significance (P<0.05). There was no statistically significant difference in NIHSS score at admission in two groups (t=0.324, P>0.05). The observation group had lower NIHSS score after 2 and 7 d of thrombolysis than the control group, and the difference had statistical significance (t=2.765, 5.790, P<0.05). Conclusion Perfection of green channel and thrombolytic process for patients with acute cerebral ischemic stroke is helpful to control thrombolytic treatment time, shorten DNT and save lives. Early intravenous thrombolysis treatment can promote recovery of neurological function in patients and improve quality of life in patients. Hospital should constantly improve the green channel and thrombolysis process according to practical situation to save lives.

【Key words】 Green channel; Thrombolytic process; Intravenous thrombolysis rate; Thrombolysis time

静脉溶栓治疗是目前临床上用于治疗缺血性脑卒中的最有效方法, 而最佳的溶栓治疗时间是在发病后的4.5 h内, DNT则在1 h, 把握时间是抢救的关键[1, 2]。但是目前国内外多数医院的DNT都在1 h以上, 这严重影响了静脉溶栓治疗的效果, 影响到患者的康复[3, 4]。因此, 惠州市第一人民医院结合实际情况完善绿色通道和溶栓流程, 有效缩短DNT, 提高抢救效果, 现汇报如下。

1 资料与方法

1. 1 一般资料 随机选取惠州市第一人民医院急诊科2016年

1~6月收治的35例急性缺血性脑卒中患者作为对照组, 2016年7~10月收治的41例急性缺血性脑卒中患者为观察组。对照组中男25例, 女10例, 年龄46~65岁, 平均年龄(53.0±4.5)岁;

观察组中男30例, 女11例, 年龄44~68岁, 平均年龄(53.8± 4.8)岁。两组患者一般资料比较, 差异无统计学意义(P>0.05), 具有可比性。……

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