王国文
摘 要 目的:探讨地佐辛联合右美托咪啶在机械通气中的应用效果。方法:选取机械通气患者112例随机分为观察和对照组各56例。对照组采用地佐辛干预镇痛,观察组采用地佐辛联合右美托咪啶镇痛,比较两组患者临床应用效果。结果:观察组镇痛干预后患者的Ramsay镇静评分和镇痛总有效率高于对照组,不良反应发生率显著低于对照组。结论:地佐辛联合右美托咪定对机械通气患者行镇痛镇静干预效果较好,可提高患者的镇静效果,提升镇痛总有效率,降低不良反应情况的发生。
关键词 地佐辛 右美托咪啶 机械通气
中图分类号:R971.3; R614.24 文献标识码:A 文章编号:1006-1533(2017)15-0032-02
Effect of dezocine combined with dexmedetomidine in the treatment of 56 cases of the patients with mechanical ventilation
WANG Guowen*
(Department of ICU, the Third Peoples Hospital of Jingdezhen City, Jindezhen 333001, China)
ABSTRACT Objective: To explore the effect of application of dezocine combined with dexmedetomidine in mechanical ventilation. Methods: One hundred and twelve patients with mechanical ventilation were randomly divided into an observation group and a control group with 56 cases each. Analgesia was performed with dezocine in the control group and dezocine combined with dexmedetomidine in the observation group. Clinical effects were compared between the two groups. Results: Ramsay sedation scores and the total analgesic efficiency were higher and the incidence of adverse reactions was significantly lower in the observation group than in the control group after analgesia. Conclusion: Dezocine combined with dexmedetomidine has good effect of analgesia and sedation on patients underwent mechanical ventilation, can improve sedation effect of the patients, enhance the total effectiveness of analgesia and reduce the occurrence of adverse reactions.
KEY WORDS dezocine; dexmedetomidine; mechanical ventilation
临床上常采用机械通气来救治多种重症疾病,但在实施过程中,患者常会感到痛苦,这是由于机械通气会对患者造成应激刺激或一定程度的疼痛,且多伴有心率和血压波动,从而导致患者治疗依从性差,影响疾病治疗效果[1]。为了进一步研究地佐辛联合右美托咪定在机械通气患者中的镇痛效果,本研究对我院收治的机械通气患者分别采用地佐辛及地佐辛联合右美托咪定镇痛。
1 资料与方法
1.1 一般资料
选取我院在2014年10月—2016年10月机械通气患者112例随机分成观察和对照组,每组各56例。排除标准:无法用药物控制血压者;服用肾上腺受体阻滞药物者;心动过缓者;严重脏器功能障碍者。其中观察组男31例,女25例,年龄24~86岁,平均(59.27±4.29)岁;对照组男29例,女27例,年龄26~85岁,平均(60.41±3.58)岁。比较两组性别、年龄等一般资料,差异均无统计学意义(P>0.05),具有可比性。……