胡秀
【摘要】 目的:对比分析连续性与间歇性血液净化治疗脓毒症所致急性肾损伤的临床效果。方法:回顾性收集60例脓毒症所致急性肾损伤患者的临床资料,根据治疗方式分为连续性血液净化组(CRRT组)和间歇性血液透析組(IHD组),比较两组患者治疗前后的血Scr与BUN水平。结果:治疗前,两组患者Scr、BUN水平比较差异无统计学意义(P>0.05);治疗后,CRRT组与IHD组Scr、BUN水平均低于治疗前,且CRRT组低于IHD组,差异均有统计学意义(P<0.05)。结论:对于脓毒症所致急性肾损伤患者而言,连续性血液净化是降低Scr及BUN水平更有效的方式。
【关键词】 血液净化; 脓毒症; 急性肾损伤
doi:10.14033/j.cnki.cfmr.2017.23.067 文献标识码 B 文章编号 1674-6805(2017)23-0130-02
Clinical Observation of Different Blood Purification Methods in Treatment of Acute Renal Injury Caused by Sepsis/HU Xiu.//Chinese and Foreign Medical Research,2017,15(23):130-131
【Abstract】 Objective:To compare and analyze the clinical effects of continuous and intermittent blood purification in the treatment of acute renal injury caused by sepsis.Method:The clinical data of 60 patients with sepsis induced acute kidney injury were collected and divided into continuous blood purification group(group CRRT) and intermittent hemodialysis group(group IHD),the levels of serum Scr and BUN were compared between the two groups before and after treatment.Result:Before treatment,there was no significant difference in Scr and BUN between the two groups(P>0.05).After treatment,the levels of Scr and BUN in CRRT group and IHD group were lower than those before treatment,and the CRRT group was lower than that in IHD group,the difference was statistically significant(P<0.05).Conclusion:Blood purification is a more effective way to reduce Scr and BUN levels in patients with sepsis induced acute kidney injury.
【Key words】 Blood purification; Septic disease; Acute kidney injury
First-authors address:Deyang Peoples Hospital,Deyang 618000,China
脓毒症是临床上常见的急危重症,多发生于大手术、严重创伤或烧伤之后,它作为一种全身性炎症反应综合征对机体多器官功能均可造成影响[1]。脓毒症病理过程中产生的过量炎症介质导致肾脏血流动力学异常,肾脏严重缺血低灌注而引发急性肾损伤,合并多器官功能衰竭的急性肾损伤死亡率高达50%~90%[2-3]。因此,探讨脓毒症所致急性肾损伤的有效治疗手段对挽救患者生命、降低死亡率至关重要。目前,临床上以血液净化作为脓毒症所致急性肾损伤的常用治疗手段,主要包括连续性与间歇性两种方式[4]。本研究对比分析连续性与间歇性血液净化治疗脓毒症所致急性肾损伤的临床效果,现报道如下。
1 资料与方法
1.1 一般资料
回顾性收集2016年1-12月笔者所在医院收治的脓毒症合并急性肾损伤的60例患者的临床资料,根据治疗方式分为连续性血液净化组(CRRT组)和间歇性血液透析组(IHD组)。CRRT组32例,男22例,女10例;年……