生化汤与益母草胶囊治疗生化汤与益母草胶囊治疗

邓宇芳

[摘要] 目的 探討生化汤与益母草胶囊治疗产后胎盘胎膜残留的对照研究。 方法 选取我院2015年1月～2017年1月收治的产后胎盘胎膜残留患者1000例，按数字表法将其随机分为生化汤组（n=500）和益母草组（n=500）。两组患者均予以注射缩宫素常规西医治疗，生化汤组给予口服生化汤治疗，益母草组给予口服益母草胶囊治疗。比较两组患者的临床治疗效果，观察两组患者治疗前后胎盘胎膜残留面积及血β-hCG水平，并比较两组患者子宫缩复情况、阴道流血持续时间以及产后出血发生率和产后清宫率。并观察两组患者治疗期间不良反应情况。 结果 生化汤组治疗有效率为93.00%（465/500）明显高于益母草组80.00%（400/500）（P<0.05）；生化汤组治疗后胎盘胎膜残留面积及血β-hCG水平较益母草组减少（P<0.05）；生化汤组治疗后B超示子宫缩复情况明显优于益母草组，并且其阴道流血持续时间、产后出血发生率和产后清宫率均较益母草组减少（P<0.05）；生化汤组胃肠道反应、心悸眩晕及皮疹等不良反应发生率为13.00%（65/500）与益母草组15.00%（75/500）比较，差异无统计学意义（P>0.05）。 结论 生化汤与益母草胶囊均可有效改善产后胎盘胎膜残留患者的临床症状，但生化汤较益母草胶囊治疗效果更显著，可有效降低产后出血情况及清宫率，加快子宫复旧的速度，且不良反应少，值得临床上推广。

[关键词] 生化汤；益母草胶囊；胎盘胎膜残留；对照研究

[中图分类号] R271.9 [文献标识码] A [文章编号] 2095-0616（2017）20-85-04

Comparative study of Shenghua decoction and motherwort caPsule in the treatment of residual of postpartum Placenta and fetal membranes

DENG Yufang

Department of Obstetrical，the First Maternal and Child Health Care Center of Huizhou City，Guangdong Province，Huizhou 516100，China

[Abstract] Objective To explore the effect of Shenghua decoction and motherwort capsule in treatment of residual of postpartum placenta and fetal membranes. Methods 1000 patients with postpartum placenta and fetal membranes who were treated in our hospital from January 2015 to January 2017 were selected.They were randomly divided into Shenghua Decoction group （n=500） and Motherwort group （n=500）.Patients of two groups were given routine western medicine treatment，such as Oxytocin injection.Shenghua Decoction group was treated with oral Shenghua decoction，and motherwort group was treated with oral motherwort capsule.The clinical effects of the two groups were compared；The residual area of placenta，fetal membranes and the levels of serum beta -hCG were observed before and after treatment in two groups；The uterine retraction，vaginal bleeding duration，the incidence of postpartum hemorrhage and the rate of postpartum curettage were compared between the two groups.The adverse reactions during the treatment were observed in the two groups. Results The effective rate of Shenghua Decoction group was 93% （465/500），which was significantly higher than that of Leonurus Decoction group 80% （400/500）（P<0.05）；After treatment，the residual area of placenta and membranes and the levels of serum beta-hCG in Shenghua Decoction group were lower than those in motherwort group （P<0.05）；After the treatment of Shenghua Decoction group，B ultrasound showed that the uterine retraction was significantly better than the motherwort group，and the duration of vaginal bleeding，the incidence of postpartum hemorrhage and the rate of postpartum curettage were lower than those in the motherwort group （P<0.05）；The incidence of adverse reactions such as gastrointestinal reaction，palpitation，vertigo and rash in Shenghua Decoction group was 13% （65/500），compared with the Motherwort group （15%）（75/500），there was no significant difference （P>0.05）. Conclusion Shenghua Decoction and motherwort capsule could effectively improve the clinical symptoms of patients with postpartum retained placenta，but compared with Shenghua Decoction，motherwort capsule treatment effect is more significant，which can effectively reduce postpartum hemorrhage and the rate of curettage of uterine involution，accelerate the speed，and less adverse reactions，it is worthy of clinical promotion.endprint

[Key words] Shenghua Decoction；Motherwort capsule；Residual Placenta and fetal membranes；Control study

产后胎盘胎膜残留是妇女产后常见的一种并发症，由产后胎盘植入、胎盘粘连引起的，易导致患者产生腹痛、阴道持续性出血以及晚期产后出血等症状的[1-2]。而症状严重患者往往需进行清宫术清将留物除残，但手术会产生较大创伤性，从而引发一系列并发症，因此，积极的寻找一种安全有效的中药制剂治疗方法对产后胎盘胎膜残留患者意义重大[3-4]。本研究探讨生化汤与益母草胶囊治疗产后胎盘胎膜残留的对照研究，取得满意效果，现报道如下。……