阿托伐他汀治疗2型糖尿病合并急性脑梗死患者的效果观察

薛美丽

DOI：10.16658/j.cnki.1672-4062.2017.13.001

[摘要] 目的 对治疗2型糖尿病合并急性脑梗死患者采用阿托伐他汀药物的临床效果进行观察与研究。方法 选取2016年10月—2017年5月在该院进行治疗的50例2型糖尿病合并急性脑梗死患者，将这些患者随机进行分组，分别是观察组与对照组，对照组患者采用常规的降糖药物进行治疗，而观察组患者采用常规治疗方式加以阿托伐他汀药物进行治疗，均进行为期1个月的治疗，并对两组患者的临床效果进行观察与比较。结果 通过对两组患者进行为期1个月的治疗，观察的治疗效果明显优于对照组患者，其中观察组的总有效率为96.30%，对照组的总有效率为69.57%，差异有统计学意义（P<0.05）；而且经过为期1个月的治疗后，两组患者的颈动脉内膜厚度都得到显著的下降，其中观察组患者的颈动脉内膜厚度比对照组患者的颈动脉内膜厚度明显低，差异有统计学意义（P<0.05）。 结论 通过对2型糖尿病合并急性脑梗死患者采用常规治疗方式加以阿托伐他汀药物进行治疗，发现患者病情得到显著改善，临床疗效明显，突显其应用价值。

[关键词] 脑梗死；2型糖尿病；阿托伐他汀；临床疗效

[中图分类号] R587 [文献标识码] A [文章编号] 1672-4062（2017）07（a）-0001-02

Observation on the Effect of Atorvastatin in Patients of Type 2 Diabetes Mellitus Complicated with Acute Cerebral Infarction

XUE Mei-li

Department of Neurology， Changle County Hospital of Traditional Chinese Medicine， Weifang，Shandong Province， 262400 China

[Abstract] Objective This paper tries to observe and study the clinical effect of atorvastatin in patients with type 2 diabetes mellitus complicated with acute cerebral infarction. Methods 50 patients with type 2 diabetes mellitus complicated with acute cerebral infarction treated in this hospital from October 2016 to May 2017 were randomly divided into the observation group and the control group. The control group was treated with routine hypoglycemic drugs， and the observation group of patients using conventional treatment and atorvastatin drugs， both for one month of treatment， and the clinical effect of the two groups of patients were observed and compared. Results After one month of treatment， the treatment effect of the observation group was significantly better than that of the control group. The total effective rate was 96.30% in the observation group and 69.57% in the control group， and the difference was significant （P<0.05）； and the carotid intima thickness of both groups was significantly decreased， and the carotid intima thickness of the observation group was significantly thinner than that of the control group， with statistical significance （P<0.05）. Conclusion The atorvastatin and conventional treatment for patients with type 2 diabetes mellitus complicated with acute cerebral infarction is effective. The clinical situation has been significantly improved， and the clinical curative effect is obvious and its application value is highlighted.

[Key words] Cerebral infarction； Type 2 diabetes mellitus； Atorvastatin； Clinical efficacy

現阶段，临床上导致急性脑梗死疾病的关键因素就是2型糖尿病，而且此病导致的致残率极高[1]。为了抑制颈动脉粥样硬化斑块的发展趋势，找到有效的治疗方法至关重要[2]。因此该文选取2016年10月—2017年5月在该院进行治疗的50例2型糖尿病合并急性脑梗死患者为研究对象，并对这两组患者采用不同的治疗药物的临床效果进行观察与分析，现报道如下。endprint

1 资料与方法

1.1 一般资料

选取2016年10月—2017年5月在该院进行治疗的50例2型糖尿病合并急性脑梗死患者为研究对象，将这些患者随机分为两组，分别是观察组与对照组。其中观察组患者为27例，有男性患者11例，女性患者16例，年龄在45～80岁之间，平均年龄为（49.32±5.21）岁；而对照组的患者为23例，有男性患者10例，女性患者13例，年龄在43～77岁之间，平均年龄为（46.33±4.87）岁。……