张淑华 夏群
【摘要】 目的:用營养不良-炎症评估(MIS)方法全面评估维持性血液透析(MHD)患者的营养状况,并找出导致营养不良的主要原因;分析患者营养不良发生的相关危险因素。方法:选取南京市浦口区中心医院101例维持性血液透析患者,根据MIS评分分为轻度营养不良组和中重度营养不良组,观察两组在生化指标及人体测量指标之间的差异。结果:轻度营养不良组与中重度营养不良组年龄、肌酐、铁蛋白、上臂围(MAC)、肱三头肌皮皱厚度(TSF)、上臂中部肌围(MAMC)、体重指数(BMI)、尿素清除率(KT/V)、改良主观综合性评估(MQSGA)等方面,差异均有统计学意义(P<0.05)。按照年龄分为老龄组和非老龄组,非老龄组尿素、肌酐、尿酸等方面均高于老龄组(P<0.05);老龄组MQSGA、MIS评分等方面均高于非老龄组,差异均有统计学意义(P<0.01)。根据C反应蛋白(CRP)水平分为CRP<1组和CRP≥1组,结果显示两组人体测量指标及评分方面比较,差异均无统计学意义(P>0.05)。MAC、TSF、MAMC、BMI、MQSGA与MIS评分有明显的相关性。结论:本院血液透析中心MHD患者整体营养状态较好。MHD患者血液透析充分,营养不良的主要原因是蛋白质摄入不足。年龄越大,越容易出现营养不良。
【关键词】 血液透析; 营养状态; 营养不良-炎症评估
Analysis of Nutritional Status in Maintenance Hemodialysis Patients/ZHANG Shuhua,XIA Qun.//Medical Innovation of China,2017,14(32):037-040
【Abstract】 Objective:To evaluate the use of malnutrition inflammation(MIS) method for comprehensive assessment of maintenance hemodialysis(MHD) patients nutritional status,and find out the main causes of malnutrition,analysis of the related risk factors of malnutrition in patients.Method:Nanjing Pukou Central Hospital,101 cases of hemodialysis patients,according to MIS they were divided into mild malnutrition group and moderate to severe malnutrition group,the differences between two groups in biochemical and anthropometric parameters were observed.Result:Age,creatinine,ferritin,MAC,upper arm circumference,triceps skinfold(TSF),mid arm muscle circumference(MAMC),body mass index(BMI),urea clearance rate(KT/V),the modified subjective comprehensive evaluation(MQSGA) of mild malnutrition group and moderate to severe malnutrition group,the differences were statistically significant(P<0.05).According to the age they were divided into aging group and non elderly group age,non aged group were higher than those of aging group in urea,creatinine and uric acid(P<0.05),aged group was higher than that of non aged group in MQSGA and MIS scores,the differences were statistically significant(P<0.01).According to C reaction protein(CRP) levels,they were divided into CRP<1 group and and CRP≥1 group,the results showed that two groups in terms of anthropometric indexes had no significant differences(P>0.05).MAC,TSF,MAMC,BMI and MQSGA were significantly correlated with MIS scores.Conclusion:The nutritional status of MHD patients in our hemodialysis center is better.Hemodialysis is the cause of malnutrition in MHD patients.The main cause of malnutrition is insufficient protein intake in patients.The older you are,the more likely you are to become malnourished.endprint
【Key words】 Hemodialysis; Nutritional status; Malnutrition inflammation evaluation
First-authors address:Nanjing Pukou Central Hospital,Nanjing 211800,China
doi:10.3969/j.issn.1674-4985.2017.32.009
血液透析是终末期肾脏病(ESRD)患者的主要治疗方式之一。维持性血液透析(MHD)延长了生命,但同时也加重了患者的营养不良。改善营养状态不仅可以降低患病率和死亡率,还可以改善生活质量[1]。因此正确评估、早期诊断和纠正影响营养不良发生发展的因素对于ESRD患者至关重要。现报道如下。
1 资料与方法
1.1 一般资料 选取2016年10月-2017年4月在南京市浦口区中心医院血液净化中心进行MHD治疗的患者。纳入标准:(1)规律血液透析6个月以上,每周2~3次;(2)近期无恶性肿瘤、传染性疾病等引起营养不良的其他因素;(3)未接受肠外营养者;(4)近期无严重水钠潴留等严重并发症者;……