神经内科癫痫病临床诊断及治疗效果分析

于笑峰 王丽

[摘要] 目的 对神经内科癫痫病临床诊断及治疗效果进行分析探讨。方法 方便选取2016年4月—2017年4月来该院神经内科治疗的癫痫病患者103例，并按照随机原则将患者分为两组。对照组51例患者行丙戍酸钠缓释片治疗，实验组52例患者在对照组治疗基础上行拉莫三嗪片治疗，治疗3个月后，对两组患者的治疗效果进行比较。 结果 对照组治疗显效21例，有效19例，无效11例，治疗有效率为78.43%。实验组治疗显效28例，有效22例，无效2例，治疗有效率为96.15%。对照组出现不良反应的患者占21.57%，实验组出现不良反应的患者占5.77%。经过比较发现，复合治疗的不良反应发生率显著低于单一治疗患者，实验组治疗有效率显著高于对照组，差异有统计学意义（P<0.05）。结论 癫痫病患者在临床表现上存在差异，在对患者临床诊断时应对患者病史及症状详细询问，综合判断后对患者予以丙戍酸钠缓释片联系拉莫三嗪片治疗，可显著缓解患者症状，并使得治疗效果更加显著，临床应用价值较大。

[关键词] 神经内科；癫痫病；临床诊断；治疗效果

[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2018）01（b）-0010-03

[Abstract] Objective To study the clinical diagnosis and treatment effect of epilepsy in the department of neurology. Methods 103 cases of patients with epilepsy admitted and treated in our hospital from April 2016 to April 2017 were conveniently selected and randomly divided into two groups， the control group with 51 cases were treated with sodium valproate retard tablet， while the experimental group with 52 cases were treated with lamotrigine tablets on the basis of the control group， and the treatment effect after three months was compared between the two groups. Results In the control group， 21 cases were markedly effective， 19 cases were effective and 11 cases were ineffective and the treatment effective rate was 78.43%， in the experimental group， 28 cases were markedly effective， 22 cases were effective， 2 cases were ineffective and the treatment effective rate was 96.15%， and the incidence rate of adverse reactions in the control group and in the experimental group was respectively 21.57% and 5.77%， and the incidence rate of adverse reactions of combined therapy was obviously lower than that of single therapy， and the treatment effective rate in the experimental group was obviously higher than that in the control group， with statistical significance（P<0.05）. Conclusion The clinical manifestations of patients with epilepsy is different， and we should inquire the disease history and symptoms in detail in clinical diagnosis of patients， thus making the treatment effect more obvious and clinical application value greater.

[Key words] Department of neurology； Epilepsy； Clinical diagnosis； Treatment effect

癲痫病是神经内科临床常见疾病，在临床上的发病率较高，患者概率约为0.6%，一年发病率约为0.4%。据调查，我国现今存在的癫痫病患者人数在600万左右，且患者多为儿童及青年，多是由脑血管疾病导致的[2]。临床对患者需早诊断、早治疗，改善预后，提高生活质量。对癫痫病患者治疗的主要方式是采取抗癫痫药物，药物控制疾病的效果较为理想，但仍有一部分患者病情服用药物后仍得不到有效控制[3]。现今，随着医疗技术的发展，临床上治疗癫痫病的方法也日益丰富，取得的成就较大。现今，临床上治愈癫痫病概率已达到90%以上。但由于癫痫病本身疾病的危害性较大，因此对患者进行及时诊断治疗仍具有十分重要的意义[4]。……