经颅磁刺激联合帕罗西汀治疗创伤后应激障碍的效果分析

2018-06-08 09:45:12李学欣夏存华
中外医疗 2018年4期

李学欣 夏存华

[摘要] 目的 研究探讨经颅磁刺激联合帕罗西汀治疗创伤后应激障碍的效果。方法 方便选择2015年3月—2017年3月聊城市复退军人医院精神科创伤后应激障碍患者80例进行研究讨论,把所有患者随机分为两组各40例,对照组采用帕罗西汀进行治疗,观察组采取颅磁刺激联合帕罗西汀对其进行治疗,观察两组患者的应激障碍量表评分(PCL)、HAMA量表评分以及治疗后患者出现不良反应的情况。结果 观察组患者治疗后的HAMA评分差为(12.19±2.31)分,对照组的为(7.89±3.17)分,观察组患者的HAMA量表评分明显的比对照组的要低,两组比较,差异有统计学意义(P<0.05)。结论 采取颅磁刺激联合帕罗西汀进行治疗,不但治疗的效果较好,还可以帮助患者改善症状,促进预后,减少不良反应的出现,可以在今后创伤后应激障碍患者的治疗过程中应用。

[关键词] 颅磁刺激;帕罗西汀;创伤后应激障碍

[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742(2018)02(a)-0117-03

Transcranial Magnetic Stimulation Combined with Paroxetine in the Treatment of Posttraumatic Stress Disorder

LI Xue-xin1, XIA Cun-hua2

1.Department of Psychiatry, Liaocheng Veterans Hospital, Liaocheng, Shandong Province, 252000 China; 2.Department of Psychiatry, Liaocheng TCM Hospital, Liaocheng, Shandong Province, 252000 China

[Abstract] Objective This paper tries to investigate the effect of transcranial magnetic stimulation combined with paroxetine in the treatment of post-traumatic stress disorder. Methods 80 patients with psychiatric post-traumatic stress disorder in this hospital from March 2015 to March 2017 were convenient selected. All patients were randomly divided into two groups of 40 cases in each. The control group was treated with paroxetine, the observation group was treated with paroxysm CT and paroxetine, and the stress disorder score (PCL), HAMA score and adverse reactions in patients after treatment were observed. Results The HAMA score of the observation group was (12.19±2.31)points and that of the control group(7.89±3.17)points, and the HAMA score of the observation group was significantly lower than that of the control group (P<0.05). Conclusion Tailored cranial magnetic stimulation combined with paroxetine can not only treat patients better, but also help patients to improve their symptoms, promote prognosis and reduce the occurrence of adverse reactions. They can be used in the treatment of post-traumatic stress disorder patients in the future.

[Key words] Magnetic stimulation; Paroxetine; Post-traumatic stress disorder

创伤后应激障碍主要是指患者在受到較大的灾难性事件之后,出现的一系列生理心理综合征[1]。该病主要的临床表现为焦虑、恐惧、没有安全感、烦躁易怒、记忆力下降、认知功能障碍以及回想创伤体验等[2]。相关研究显示,帕罗西汀可以帮助患者改善其焦虑、抑郁等症状,改善患者的社会功能。经颅磁刺激是一种无痛、无创的生物技术,可帮助患者刺激脑组织,诱发出感应电流,从而改变神经细胞电位,促进代谢和神经电活动[3]。该次试验方便选择了2015年3月—2017年3月80例创伤后应激障碍患者进行分组研究,现报道如下。

1 资料与方法

1.1 一般资料

选方便择该院创伤后应激障碍患者80例进行研究讨论,把所有患者随机分为两组,两组都为40例,对照组男性22例,女性18例,年龄18~60岁,平均年龄(32.3±13.9)岁;……

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