右美托咪定联合丙泊酚麻醉在老年无痛胃镜麻醉中的应用效果

连志鹏 张铨

[摘要]目的 對比分析老年无痛胃镜麻醉中单纯应用丙泊酚与其联合右美托咪定的临床效果。方法 将我院2016年3月～2017年9月接受无痛胃镜检查的88例老年患者作为观察对象，依照硬币法分为对照组（n=44）和观察组（n=44）。对照组患者予以丙泊酚麻醉，观察组患者予以丙泊酚联合右美托咪定麻醉，对两组患者麻醉诱导时间、苏醒时间、检查中并发症及检查后不良反应发生情况予以统计比较。结果 观察组患者麻醉诱导时间、苏醒时间短于对照组，分别为（133.8±19.4）s vs.（147.7±20.6）s、（95.2±16.2）s vs.（116.5±22.4）s，差异有统计学意义（P<0.05）。观察组患者并发症发生率低于对照组，分别为4.5%、18.2%，两组差异有统计学意义（P<0.05）。观察组患者不良反应发生率为4.5%，与对照组患者（11.4%）比较，差异无统计学意义（P>0.05）。结论 老年无痛胃镜麻醉应用丙泊酚联合右美托咪定的效果更加显著，不仅可缩短麻醉诱导时间与苏醒时间，还可减少并发症的发生，具有安全、可靠的特点，值得在临床中与推广与应用。

[关键词]无痛胃镜；丙泊酚；右美托咪定；麻醉

[中图分类号] R614 [文献标识码] A [文章编号] 1674-4721（2018）4（c）-0070-03

Effect of Dexmetomidine combined with Propofol anesthesia on senile painless gastroscopy

LIAN Zhi-peng ZHANG Quan

Department of Anesthesiology，95th Hospital of PLA，Fujian Province，Putian 351200，China

[Abstract]Objective To compare the clinical effect of gastroscopy anesthesia in the elderly treated with Propofol combined with Dexmedetomidine.Methods A total of 88 elderly patients who received painless gastroscopy during the period from March 2016 to September 2017 were selected as observation subjects，and they were divided into control group（n=44） and observation group（n=44） according to the coin method.The control group patients were given Propofol anesthesia，the observation group patients were given Propofol combined Dexmetomidine on anesthesia，two groups of patients anesthesia induction time，recovery time，check the complications and adverse reactions after the test were compared.Results The observation group of patients anesthesia induction time，wake up of time was shorter than that in the control group patients，data respectively（133.8±19.4） s vs.（147.7±20.6） s，（95.2±16.2） s vs. （116.5±22.4） s，the two groups was statistically difference（P<0.05）.The incidence of complications in the observation group was lower than that in the control group，and the data were 4.5% and 18.2%，respectively，and the comparison of the two groups was statistically significant（P<0.05）.The incidence of adverse reactions in the observation group was 4.5%，compared with 11.4% in the control group，no statistical difference（P>0.05）.Conclusion The effect of Propofol combined with Dexmedetomidine in elderly patients with painless gastroscopy anesthesia is more significant，not only can shorten the induction time and recovery time of anesthesia，but also can reduce the occurrence of complications，with safe and reliable features，it is worth in the clinical further application and promotion.