女性肥胖不孕症患者治疗前后血浆瘦素和血清胰岛素、睾酮水平检测的临床意义

2018-08-31 09:58:16王彬
中外医疗 2018年13期

王彬

[摘要] 目的 探討女性肥胖不孕症患者治疗前后血浆瘦素(Leptin)和血清胰岛素(Ins)、睾酮(T)水平检测的临床意义。方法 方便选取该院在2015年6月—2016年5月期间诊治的33例女性肥胖不孕症患者作为研究对象,定为研究组,治疗前后使用放射免疫分析法进行血浆瘦素和血清胰岛素、睾酮水平检测,并将监测结果与同期来该院检查的正常女性(33例,对照组)进行对比。 结果 研究组血浆 Leptin 值为(19.88±3.56)ng/mL,血清 Ins值为(22.73±6.65)nU/mL,T 值为(2.74±1.14)μg/L,而对照组血浆 Leptin 值为(8.87±2.18)ng/mL,血清 Ins值为(10.43±4.32)nU/mL,T 值为(1.17±0.52)μg/L,由此可见,研究组各项指标水平均明显高于对照组,差异有统计学意义(t=13.578 4 、18.356 7、8.049 4,P<0.05);治疗前,研究组患者血浆 Leptin 值为(19.88±3.56)ng/mL,血清 Ins值为(22.73±6.65)nU/mL,T 值为(2.74±1.14)μg/L,治疗后,患者血浆 Leptin 值为(14.47±2.15)ng/mL,血清 Ins值为(17.45±6.14)nU/mL,T 值为(1.76±0.44)μg/L,治疗前后对比差异有统计学意义(t=7.346 7、8.863 2、8.543 2,P<0.05)。 结论 对女性肥胖不孕症患者在治疗前后进行血浆瘦素和血清胰岛素、睾酮水平检测具有重要的现实意义,为临床治疗提供科学的依据。

[关键词] 女性肥胖;不孕症;血浆瘦素;血清胰岛素;睾酮

[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742(2018)05(a)-0022-03

Clinical Significance of Testing the Plasma Leptin, Serum Insulin and Testosterone of Female Patients with Obesity Sterility

WANG Bin

Department of Gynecology, Dalin First Peoples Hospital, Dali, Yunnan Province, 671000 China

[Abstract] Objective To study the clinical significance of testing the plasma leptin, serum insulin and testosterone of female patients with obesity sterility. Methods 33 cases of females patients with obesity sterility admitted and treated in our hospital from June 2015 to May 2016 were convenient selected as the research group, and the plasma leptin, serum insulin and testosterone of female patients with obesity sterility were tested before and after treatment by the radioimmunoassay, and the monitoring results were compared with the normal females with 33 cases in the control group. Results The plasma Leptin value, serum Ins, T value in the research group were obviously higher than those in the control group[(19.88±3.56) ng/mL, (22.73±6.65)nU/mL, (2.74±1.14) μg/L vs (8.87±2.18) ng/mL, (10.43±4.32) nU/mL, (1.17±0.52) μg/L],and the differences were statistically significant(t=13.578 4,18.356 7,8.049 4,P<0.05), before treatment, the plasma Leptin value, serum Ins, T value in the research group before treatment and after treatment were respectively (19.88±3.56)ng/mL,(22.73±6.65) nU/mL,(2.74±1.14) μg/L, and ( 14.47±2.15) ng/mL, (17.45±6.14) nU/mL, (1.76±0.44) μg/L, and the differences were statistically significant (t=7.346 7,8.863 2,8.543 2, P<0.05). Conclusion The test of the Plasma Leptin, serum insulin and testosterone of female patients with Obesity sterility is of important realistic significance, thus providing scientific basis for the clinical treatment.

[Key words] Female obesity; Sterility; Plasma Leptin; Serum insulin; Testosterone

女性肥胖不孕症是临床上常见的一种疾病,需要积极进行治疗。而为了确定具体的治疗方案,一定要在治疗前后进行全面检测,主要包括血浆瘦素和血清胰岛素、睾酮水平[1-2]。该文将该院在2015年6月—2016年5月期间诊治的33例女性肥胖不孕症患者作为研究对象进行分析,结果报道如下。

1 资料与方法

1.1 一般资料

资料方便选取于该院诊治的33例女性肥胖不孕症患者,定为研究组,年龄25~33岁,平均(27.56±4.45)岁,结婚时间均在2年以上。选择同期来该院检查的33名体重和月经均正常的女性作为对照组,年龄25~33岁,平均(27.56±4.45)岁。该次研究通过了医院伦理委员会的批准同意,所有患者均自愿参与该次研究,并签署了知情同意书。两组患者在一般资料上对比差异无统计学意义(P>0.05),具有可比性。

1.2 方法

对所有研究对象均在清晨空腹状态下抽取静脉血6 mL,其中一管加 EDTA。……

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