前列舒通胶囊联合乙酰半胱氨酸治疗精液不液化54例临床观察

李艳春

【摘 要】 目的：观察前列舒通胶囊联合乙酰半胱氨酸治疗精液不液化的临床效果。方法：选取精液不液化患者108例为研究对象，随机分为对照组和研究组各54例。对照组口服乙酰半胱氨酸片，研究组在对照组基础上联合前列舒通胶囊。1个疗程后，比较两组疗效、不良反应及治疗前后精液液化时间。结果：研究组总有效率为92.6%，显著高于对照组的75.9%，治疗后精液液化时间显著短于对照组，差异有统计学意义（P<0.05）；两组不良反应差异无统计学意义（P>0.05）。结论：前列舒通胶囊联合乙酰半胱氨酸治疗精液不液化的临床效果显著，可促进精液液化，且安全性佳，值得在临床推广应用。

【关键词】 精液不液化；前列舒通胶囊；乙酰半胱氨酸

【中图分类号】R256.56 【文献标志码】 A【文章编号】1007-8517（2018）11-0112-02

Abstract：Objective To observe the clinical effect of Qianlie Shutong capsule combined with acetylcysteine treating 54 cases semen uliquefaction. Methods 108 cases of semen uliquefactionselected in our hospital were randomly divided into control group and research group， each 54 patients. Patients in control group were given acetylcysteine， and patients in research group were given Qianlie Shutong capsule based on the control group. After one course， efficacy， adverse reactions， the time of patients' semen Liquefaction before and after treatment were compared between two groups. Results The total effective rate of researchgroup was 92.6%，which was significantly higher than that of control group 75.9%， after treatment， the time of semen Liquefactionof research group were significantly shorter than that of control group， and the difference have statistical sense， there was no significant difference in the prevalence of adverse effects between two groups. Conclusion The effect of Qianlie Shutong capsule combined with acetylcysteine treating 54 cases semen uliquefaction was remarkable， and it can benefit semen liquefaction， and have good safety，it is worthy of clinical application.

Keywords：Semen Uliquefaction； Qianlie Shutong Capsule； Acetylcysteine Treating

精液不液化是指精液排出體外后，在室温下60 min仍不液化，精液粘稠似胶冻状，影响精子活力，降低精子穿透宫颈黏液的能力，不能顺利通过女性生殖道到达输卵管，与卵子完成受精[1]。该病是导致男性不育的重要原因之一，占男性不育症的2.5%～42.7%[2]。西医治疗主要是采用维生素、抗生素等药物治疗前列腺炎[3]，总体效果不佳。我院采用中药前列舒通胶囊联合西药乙酰半胱氨酸治疗精液不液化，观察临床效果，现报道如下。

1 资料与方法

1.1 一般资料 选取2016年1月至2017年11月我院收治的精液不液化患者108例为研究对象，诊断符合《人类精液及精子-宫颈黏液相互作用实验室检验手册》[4]中关于精液不液化的标准。随机将患者分为对照组和研究组各54例。其中对照组年龄23～40岁，平均（32.1±3.8）岁；……