糖化血红蛋白联合空腹血糖检测在妊娠糖尿病筛查中的应用价值

宋丽丽

[摘要] 目的 探讨妊娠糖尿病诊断中空腹血糖与糖化血红蛋白检验的应用价值。方法 选择该院2014年4月—2017年9月间收治的42例确诊妊娠糖尿病患者作为研究对象，同时纳入健康孕妇42例作为对照。妊娠糖尿病患者命名实验组，身体正常人群命名为对照组，对所有研究对象分别使用糖化血红蛋白检验和空腹血糖诊断方案，对比血糖指标。 结果 实验结果显示，实验组患者的糖化血红蛋白和空腹血糖较对照组明显更高，组间差异有统计学意义（P<0.05）。 结论 糖化血红蛋白检验与空腹血糖均能够准确的诊断出妊娠糖尿病，对于妊娠糖尿病患者的诊断来说有十分积极的意义，为患者的临床治疗提供参考和帮助。

[关键词] 妊娠糖尿病；空腹血糖；糖化血红蛋白检验；应用价值

[中图分类号] R714.256；R446.1 [文献标识码] A [文章编号] 1672-4062（2018）06（b）-0197-02

Application Value of Glycosylated Hemoglobin Combined with Fasting Blood Glucose Test in Screening for Gestational Diabetes

SONG Li-li

Department of Clinical Laboratory， Mudanjiang Women and Children's Hospital， Mudanjiang， Heilongjiang Province， 157000 China

[Abstract] Objective To investigate the application value of diagnosis of gestational diabetes mellitus with hollow blood glucose and glycosylated hemoglobin. Methods Forty-two patients with confirmed gestational diabetes who were admitted to the hospital from April 2014 to September 2017 were enrolled as subjects. 42 healthy pregnant women were included as control group. The gestational diabetes patients were named experimental group， and the normal human body was named as the control group. Glycosylated hemoglobin test and fasting blood glucose diagnosis program were used for all subjects， and the blood glucose index was compared. Results The experimental results showed that the glycosylated hemoglobin and fasting blood glucose of the experimental group were significantly higher than the control group， and the difference between the groups was statistically significant （P<0.05）. Conclusion Both glycosylated hemoglobin test and fasting blood glucose can accurately diagnose gestational diabetes， which is very positive for the diagnosis of gestational diabetes patients， and provides reference and help for clinical treatment of patients.

[Key words] Gestational diabetes mellitus； Fasting blood glucose； Glycosylated hemoglobin test； Application value

妊娠糖尿病是一種产妇在妊娠期间以高血糖为特征的代谢性疾病，其原因包含：家族遗传、环境影响、饮食习惯、生活方式等[1]。糖尿病患者主要症状为口渴、饥饿、尿频、体重下降等症状，且血糖增高；而临床来说，2型糖尿病通常以老年人居多，肥胖者发病率最高，可引起高血压、血脂异常等疾病；而孕妇也属于糖尿病的高发人群，其发病早期症状不明显，可能会感到口渴、疲惫、血糖轻微增高，此时需检验才能确诊[2]。如果孕妇在妊娠期患有糖尿病而不加以控制，则会大大增加其早产率，增加婴儿患有内分泌疾病的几率。目前最常见的检验方法即空腹血糖和糖化血红蛋白检验，为研究其应用价值，该文特选择该院2014年4月—2017年9月间收治的42例确诊妊娠糖尿病患者进行调查研究，现报道如下。

1 资料与方法

1.1 一般资料