尿微量白蛋白和尿糖检测对糖尿病早期肾损伤的临床意义分析

2018-12-08 14:54:18周琛
医学信息 2018年16期

周琛

摘   要:目的  分析尿微量白蛋白和尿糖檢测对糖尿病早期肾损伤的临床意义。方法  选取我院2015年4月~2018年3月53例2型糖尿病早期肾损伤患者作为观察组,选取同期50例健康体检者作为对照组,对比两组受检者尿微量白蛋白和尿糖检测结果。结果  观察组患者尿微量白蛋白阳性率、尿糖阳性率分别为94.34%、92.45%,均高于对照组的4.00%、6.00%,组间比较,差异具有统计学意义(P<0.05)。观察组尿糖含量、尿微量白蛋白含量分别为(1.99±0.74)mmol/L、(42.56±7.46)mg/L,均高于对照组的(1.03±0.20)mmol/L、(12.89±3.87)mg/L,差异具有统计学意义(P<0.05)。结论  糖尿病早期肾损伤患者体内环境发生明显变化,其尿微量白蛋白和尿糖含量均明显高于健康人群,及时对尿微量白蛋白和尿糖两种指标进行检测,对提示糖尿病患者是否合并早期肾损伤具有重要作用。

关键词:尿微量白蛋白;尿糖;糖尿病早期肾损伤

中图分类号:R587.1                                    文献标识码:A                              DOI:10.3969/j.issn.1006-1959.2018.16.051

文章编号:1006-1959(2018)16-0159-03

Clinical Significance of Urinary Microalbumin and Urine Glucose in Early Renal Injury in Diabetes Mellitus

ZHOU Chen

(Department of Clinical Laboratory,the Second Hospital Affiliated to Tianjin Medical University,Tianjin 300211,China)

Abstract:Objective  To analyze the clinical significance of urinary microalbumin and urine glucose in early renal injury of diabetes mellitus.Methods  From April 2015 to March 2018,53 patients with early renal injury of type 2 diabetes mellitus were selected as observation group and 50 healthy person as control group at the same time.The results of urinary microalbumin and urine  glucose were compared between the two groups.Results  The positive rates of urinary microalbumin and urine glucose in the observation group were 94.34% and 92.45%,respectively,which were higher than those in the control group 4.00%,6.00%,the difference between the two groups was statistically significant(P<0.05).The levels of urine glucose and urinary microalbumin in the observation group were(1.99±0.74)mmol/L,(42.56±7.46)mg/L,respectively,which were significantly higher than those in the control group(1.03±0.20)mg/L,(12.89±3.87)mg/L,the difference was statistically significant(P<0.05).Conclusion  The contents of urinary microalbumin and urinary glucose in diabetic patients with early renal injury were significantly higher than those in healthy people.The timely detection of urinary microalbumin and urinary glucose was important to indicate whether diabetic patients complicated with early renal injury.

Key words:Urinary microalbumin;Urine glucose;Early renal injury in diabetes mellitus

2型糖尿病(type 2 diabetes mellitus,T2DM)属于全身代谢性障碍慢性基础病,对患者身心健康具有明显影响。若未能及时开展对症治疗,则会导致血糖水平长期处于异常状态,可引发多种并发症,如糖尿病眼病、糖尿病肾病等。其中,糖尿病肾病可引发肾损伤,不仅会加重病情,还会增加临床治疗难度,对患者生命安全具有显著威胁。本研究选取我院2015年4月~2018年3月53例2型糖尿病早期肾损伤患者及50例健康体检者作为研究对象,分析其尿微量白蛋白和尿糖检测结果,现报道如下。

1资料与方法

1.1一般资料  选取2015年4月~2018年3月天津医科大学第二医院收治的53例2型糖尿病早期肾损伤患者作为观察组,本研究经医院伦理会批准,所选病例均满足糖尿病肾损伤相关诊疗标准[1],其中男性23例,女性30例,年龄48~79岁,平均年龄(65.23±3.57)岁;糖尿病病程3~18年,平均病程(8.56±2.89)年。同时,选取同期50例健康体检者作为对照组,其中男性20例,女性30例,年龄50~76岁,平均年龄(65.47±3.17)岁。两组性别、年龄等一般资料比较,差异无统计学意义(P>0.05),具有可比性。……

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