尤忠


[摘要] 目的 分析重症肺炎支原体肺炎患儿采用糖皮质激素治疗的临床效果。方法 方便选取该院2015年10月—2017年9月收治的80例重症肺炎支原体肺炎患儿,按照随机抽签法分为实验组(40例,常规治疗基础上采用糖皮质激素治疗)和对照组(40例,采用常规治疗),对比两组患儿咳嗽、退热时间、住院时间以及治疗总有效率。结果 实验组患儿退热时间(2.2±0.7)d、咳嗽时间(3.2±1.0)d、住院时间(6.3±2.1)d等指标均显著短于对照组(5.3±0.9)、(6.4±1.2)、(9.4±2.8)d,两组差异有统计学意义(t=7.498、7.802、8.501,P<0.05)。实验组患儿治疗总有效率(95.0%)显著高于对照组(72.5%),两组差异有统计学意义(χ2=7.601,P<0.05)。结论 重症肺炎支原体肺炎患儿采用糖皮质激素治疗的临床效果良好,可有效改善患儿临床症状,值得广泛推广应用。
[关键词] 重症肺炎支原体肺炎;糖皮质激素;甲泼尼龙;临床分析
[中图分类号] R563 [文献标识码] A [文章编号] 1674-0742(2018)09(a)-0099-03
Clinical Analysis of Glucocorticoid Therapy for Severe Pneumonia Mycoplasma Pneumonia
YOU Zhong
Department of Pediatrics, the Fifth Peoples Hospital of Wuxi, Wuxi, Jiangsu Province, 214000 China
[Abstract] Objective To analyze the clinical effect of glucocorticoid treatment in children with severe pneumonia mycoplasma pneumonia. Methods 80 children with severe mycoplasma pneumoniae pneumonia admitted to the hospital from October 2015 to September 2017 were conveniently selected and randomly divided into experimental group(40 cases, routine treatment based on glucocorticoid treatment) and control group(40 cases, conventional treatment was used) to compare the cough, fever duration, length of stay, and total treatment efficiency between the two groups. Results In the experimental group, the fever time (2.2±0.7)d, cough time (3.2±1.0)d, hospitalization time (6.3±2.1)d and other indicators were significantly shorter than the control group (5.3±0.9)d, (6.4±1.2)d, (9.4±2.8)d, the difference between the two groups was significant (t=7.498, 7.802, 8.501, P<0.05). The total effective rate of treatment in the experimental group(95.0%) was significantly higher than that in the control group (72.5%), and the difference was significant between the two groups (χ2=7.601, P<0.05). Conclusion The clinical effect of glucocorticoid treatment for children with severe pneumonia mycoplasma pneumonia is good, which can effectively improve the clinical symptoms of children, and it is worthy of extensive application.
[Key words] Severe pneumonia mycoplasma pneumonia; Glucocorticoid; Methylprednisolone; Clinical analysis
肺炎支原體是临床儿科较为常见的一种呼吸道感染性疾病,临床主要采用抗生素进行抗感染治疗[1]。但近年来患儿对大环内酯类抗生素的耐药性越来越高,机体免疫因素影响以及混合感染等导致重症肺炎支原体肺炎的发病率越来越高[2]。为分析重症肺炎支原体肺炎患儿采用糖皮质激素治疗的临床效果,该文对比分析了该院2015年10月—2017年9月收治的80例重症肺炎支原体肺炎患儿分别采用常规治疗以及加用糖皮质激素治疗的临床效果。
1 资料与方法
1.1 一般资料
方便选取该院收治的80例重症肺炎支原体肺炎患儿,所有患儿均通过临床诊断确诊,经实验室检查发现MP-lgM呈阳性,患儿及其家属均自愿签署知情同意书,并通过伦理委员会的批准,排除伴有胸腔积液患儿以及对本次治疗药物过敏患儿。现将80例患儿按照随机抽签法分为实验组(40例)和对照组(40例),实验组中男22例,女18例;患儿年龄9个月~12岁,平均(7.3±1.8)岁;患儿病程3~10 d,平均(5.3±2.1)d。……