淋巴结检取对Ⅱ期结肠癌根治术患者预后的影响

袁继全 赵兰君

【摘要】 目的：分析Ⅱ期结肠癌根治术患者行淋巴结检取对预后效果的影响。方法：回顾分析笔者所在医院2016年1-12月收治的行Ⅱ期结肠癌根治术患者临床资料，从中抽选出40例患者设为对照组，术中未对患者开展淋巴结检取。另选择2017年1-12月收治的40例Ⅱ期结肠癌根治术患者为观察组，术中对患者开展淋巴结检取。对比两组术后并发症发生率、术后1年生存率及术前、术后1年SF-36评分。结果：观察组术后1年生存率为82.50%，明显高于对照组的60.00%，差异有统计学意义（P<0.05）。观察组术后并发症发生率低于对照组，术后1年SF-36评分高于对照组，差异均有统计学意义（P<0.05）。结论：对Ⅱ期结肠癌根治术患者行淋巴结检取有助于提高术后生存率，提升患者的生活质量，降低并发症发生率，延长患者生存時限，应用价值较高，值得推荐。

【关键词】 结肠癌 Ⅱ期结肠癌根治术 淋巴结检取数目 预后 生存率

doi：10.14033/j.cnki.cfmr.2019.30.012 文献标识码 B 文章编号 1674-6805（2019）30-00-02

[Abstract] Objective： To analysis the effect of lymph node inspection on prognosis in patients with stage Ⅱ colon cancer. Method： Retrospective analysis the clinical data of patients who underwent radical resection for stage Ⅱ colon cancer in our hospital from January to December 2016， and 40 patients were selected as the control group， and intraoperative lymph node inspection was not performed. Another choice of 40 patients underwent radical resection for stage Ⅱ colon cancer from January to December 2017 as the observation group， and intraoperative lymph node inspection was performed. The incidence of postoperative complications， postoperative survival rate of 1 year， preoperative and postoperative SF-36 score of 1 year were compared between the two groups. Result： The postoperative survival rate of 1 year in the observation group was 82.50%， which was significantly higher than 60.00% of the control group， and the difference was statistically significant （P<0.05）. The incidence of postoperative complications in the observation group was lower than that of the control group， and postoperative SF-36 score of 1 year was higher than that of the control group， and the differences were statistically significant （P<0.05）. Conclusion： Lymph node inspection in patients undergoing radical resection for stage Ⅱ colon cancer helps to improve the postoperative survival rate， improve the quality of life of patients， reduce the incidence of complications and prolong survival time， which has higher application value and is worth to recommend.

[Key words] Colon cancer Radical resection for stage Ⅱ colon cancer Number of lymph nodes inspect Prognosis Survival rate

First-authors address： The Central Hospital of Xiaogan， Xiaogan 432000， China

结直肠癌作为临床上常见的消化系统恶性肿瘤之一，已成为全球性公共卫生问题。随着我国国民经济水平不断提高，人们的生活方式、饮食习惯等均发生较大的转变，导致结直肠癌发病率明显上升。结直肠癌包括结肠癌和直肠癌，目前主要采用外科手术、放疗、化疗等方式改善患者病情[1-2]。结肠癌的发病原因尚未明确，临床认为与环境因素、自身遗传因素等多种因素均存在密切关系。结肠癌在男性中的发病率略高于女性，早期临床表现并不明显，随着肿瘤体积不断增加，导致患者逐渐发生排便习惯改变、便血、腹泻、便秘、局部疼痛等症状，严重者还会出现贫血、体重下降等症状，具有较高的死亡率[3-4]。随着医学不断发展进步，结肠癌患者在手术治疗后能够取得良好的临床效果。相关研究表明，对Ⅱ期结肠癌根治术患者行淋巴结检取可以延长患者预后生存期限[5]。……