杜泉 乔西民 徐晓峰 李楠 张少杰 肖湘 石晓志
[摘要] 本文回顾分析1例晚期前列腺癌伴单侧睾丸转移患者。本例患者以乏困、纳差为主诉入院,诊断为前列腺癌。前列腺穿刺活检为Gleason分级8分,转至泌尿外科,2018年1月4日行双侧睾丸切除术,术后病理发现前列腺癌睾丸左侧转移。前列腺癌睾丸转移为罕见病例,缺乏诊断特征,故提示对于晚期前列腺癌患者,应注意前列腺癌睾丸转移的发生。
[关键词] 前列腺癌;睾丸转移;睾丸切除
[中图分类号] R697 [文献标识码] A [文章编号] 1673-7210(2019)03(c)-0174-03
[Abstract] This article retrospectively analyzed a patient with advanced prostate cancer with unilateral testicular metastasis. This patient was admitted to hospital with a lack of sleep and anorexia. He was diagnosed with prostate cancer. The prostate biopsy was graded 8 points by Gleason and transferred to urology on January 4, 2018. Both sides of the orchiectomy were performed. Prostate cancer testicular metastasis is a rare case and lacks diagnostic features, so it is suggested that for patients with advanced prostate cancer, attention should be paid to prostate cancer testicular metastasis.
[Key words] Prostate cancer; Testicular metastasis; Orchiectomy
前列腺腺癌在男性人群中发病率较高,最常见的远处转移部位是淋巴结、骨和肺[1]。睾丸转移是罕见的,发生率低于4%[2]。这种类型的转移通常是单侧的,表现为可触及的睾丸肿块,很少同时累及睾丸和附睾[3]。目前,关于前列腺癌睾丸转移的报道不多,使得临床医生对该病的临床表现及诊断了解不足[4]。现报道1例前列腺癌睾丸转移患者,并结合文献对该疾病进行回顾性分析,以提高临床医生对该病的认识。
1 病例资料
患者,男57岁,因“乏困、纳差,贫血2月余”于2018年1月2日收治陕西省咸阳市中心医院(以下简称“我院”)血液科。实验室检查:血常规、肝肾功能正常,游离前列腺抗原>50.00 ng/mL,总前列腺特异性抗原:1426 ng/mL;胸部CT:①右肺上叶及中叶结节灶,部分已钙化;②双下肺纤维条索灶;③右侧胸腔少量积液,双侧局部胸膜肥厚。核磁共振成像(MRI):①前列腺增生,左侧外周带区小结节灶,弥散受限;②双侧耻骨、坐骨内异常信号灶,弥散轻度受限,转移瘤可能。骨……