内镜下注射不同药物治疗消化性溃疡急性出血的效果比较

丰琳

【摘要】目的：分析采用不同药物内镜下注射治疗消化性溃疡急性出血的临床疗效。方法： 回顾性分析我院2017年10月-2018年10月期间收治的消化性溃疡急性出血患者100例临床资料，根据内镜下治疗用药的不同分成两组，立止血组50例，肾上腺素组50例。对比两组患者止血效果、呕血及黑便次数。结果：立止血组和肾上腺素组的即时止血率分别为94%和92%，再出血率分别为8%和6%，差异无统计学意义（P>005）；比较治疗后1周内两组患者发生的呕血及黑便次数，差异无统计学意义（P>005）。结论：采用立止血或肾上腺素不同药物治疗消化性溃疡急性出血的临床效果相当，均可减轻临床症状。

【关键词】消化性溃疡急性出血；内镜检查；注射；立止血；肾上腺素

【中图分类号】R573.2

【文献标志码】A

【文章编号】

1005-0019（2019）16-012-01

Abstract

objective： to analyze the clinical efficacy of endoscopic injection of different drugs in the treatment of acute hemorrhage of peptic ulcer. Methods： clinical data of 100 cases of acute hemorrhage of peptic ulcer admitted to our hospital from October 2017 to October 2018 were retrospectively analyzed. According to the different medication of endoscopic treatment， the patients were divided into two groups， 50 cases in lizhi hemostasis group and 50 cases in epinephrine group. Hemostatic effect， hematemesis and frequency of black stool were compared between the two groups. Results： the immediate hemostasis rate was 94% and 92% in the stator hemostasis group and 92% in the epinephrine group， and the re-bleeding rate was 8% and 6%， respectively. The difference was not statistically significant （P > 005）. The frequency of hematemesis and black stool in the two groups within 1 week after treatment was compared， and the difference was not statistically significant （P > 005）. Conclusion： the clinical effect of treating acute hemorrhage of peptic ulcer with different drugs of stator hemostasis or epinephrine is comparable and can reduce the clinical symptoms.

Key words：

acute hemorrhage of peptic ulcer； Endoscopic examination； Injection； Set the bleeding； adrenaline

臨床上对于消化性溃疡出血的治疗措施很多，内镜注射药物止血是目前所有非手术治疗方案中最常用之一，对于消化道溃疡急性出血临床上所使用的治疗药物也多种多样，常见包括立止血、肾上腺素、生理盐水等[1]。为对比不同药物的治疗效果，本研究回顾性分析内镜下注射立止血、肾上腺素治疗消化性溃疡急性出血的效果。现报道如下。

1资料与方法

11一般资料回顾性分析我院2017年10月-2018年10月期间收治的消化性溃疡急性出血的患者100例临床资料，根据治疗用药的不同分成两组，立止血组50例，肾上腺素组50例。所有患者均经检查确诊为消化性溃疡急性出血，均有活动性出血病史，均已排除心脑血管、肝肾功能衰竭及消化道肿瘤等影响本研究治疗药物分析的疾病，且对本研究所用治疗药物无禁忌。立止血组……