外科治疗甲状腺功能亢进症的临床效果分析

彭东杰 胡超华

【摘要】 目的：分析外科治疗甲状腺功能亢进症（简称甲亢）的临床效果。方法：选取2015年8月-2018年8月本院收治的80例甲亢患者，按照随机数字表法将其分为A组（n=40）与B组（n=40）。A组给予常规药物保守治疗，B组在A组基础上给予外科手术治疗。对比两组临床治疗效果、不良反应、治疗前后的TSH与FT4水平的变化。结果：B组总有效率为97.50%，高于A组的77.50%（字2=7.314，P=0.014）;B组不良反应发生率为2.50%，低于A组的17.50%（字2=5.000，P=0.025）;治疗后，两组TSH与FT4水平均较治疗前改善，且B组TSH与FT4水平均优于A组，差异均有统计学意义（P<0.05）。结论：相较于药物保守治疗，对甲亢患者给予外科手术治疗，不仅能够有效提高临床的治疗效果，且能在降低不良反应发生率的同时，使机体TSH与FT4水平恢复正常，对促进患者身体康复有着至关重要的作用，值得临床推广。

【关键词】 甲亢; 外科治疗; 临床效果

【Abstract】 Objective：To analyze the clinical effect of surgical treatment of hyperthyroidism.Method：A total of 80 patients with hyperthyroidism admitted to our hospital from August 2015 to August 2018 were selected，according to the method of digital random table，they were divided into group A（n=40） and group B（n=40）.Group A was treated with conventional medicine and group B was treated with surgery on the basis of group A.The clinical efficacy，adverse reactions，changes of TSH and FT4 levels before and after treatment between two groups were compared.Result：The total effective rate in group B was 97.50%，higher than 77.50% in group A（字2=7.314，P=0.014）.The incidence of adverse reactions in group B was 2.50%，lower than 17.50% in group A（字2=5.000，P=0.025）.After treatment，the levels of TSH and FT4 in both groups were improved compared with those of before treatment，and the levels of TSH and FT4 in group B were better than those of group A，the differences were statistically significant（P<0.05）.Conclusion：Compared with drug conservative treatment，surgical treatment for hyperthyroidism patients can not only effectively improve the efficiency of clinical treatment，but also reduce the incidence of adverse reactions，at the same time，make the body TSH and FT4 levels return to normal，which plays a vital role in promoting the physical recovery of patients，and is worthy of clinical promotion.

【Key words】 Hyperthyroidism; Surgical treatment; Clinical effect

First-authors address：Xiaogan Central Hospital Affiliated to Wuhan University of Science and Technology，Xiaogan 432000，China

doi：10.3969/j.issn.1674-4985.2019.17.027

甲狀腺功能亢进症（简称甲亢）是临床中较为常见的疾病之一。相关医学临床研究表明，甲亢是指当人体受到外部原因或是机体内部原因影响所导致的甲状腺功能异常，会致使机体血液循环中存在的甲状腺激素分泌量增加[1]，进而导致消化系统与自身神经系统呈现出过度兴奋状态的一种代谢性病症。在医学临床中，将甲亢分为三种类型：高功能腺瘤、继发性甲亢以及原发性甲亢[2]。在传统的临床治疗中，针对甲亢患者主要给予药物保守治疗[3]。而相关医学临床研究结果表明，相较于药物保守治疗，对患者给予外科手术治疗效果更显著，也是现代医学临床治疗甲亢患者的主要手段[4]。基于此，为了进一步分析外科治疗甲亢的临床效果，本研究选取2015年8月-2018年8月本院收治的80例甲亢患者为研究对象，按照随机数字表法将其分为两组展开研究分析，现报道如下

1 资料与方法