复合维生素B治疗口腔溃疡的临床效果

梅放

[摘要]目的 观察口腔溃疡治疗中复合维生素B的应用效果。方法 选取2018年6月～2019年6月我院收治的80例口腔溃疡患者作为研究对象，根据门诊就诊日期单双号分为研究组与对照组，每组40例。研究组患者使用复合维生素B，对照组使用维生素B6，对比两组的治疗效果。结果 研究组的临床总有效率为97.5%，高于对照组的82.5%，差异有统计学意义（P<0.05）。研究组患者的VAS疼痛评分低于对照组，症状消失时间、治疗总时间短于对照组，差异有统计学意义（P<0.05）。结论 复合维生素B在口腔溃疡的治疗中发挥着重要作用，能促进溃疡愈合，缩短治疗时间，尽快减轻病症和疼痛感，临床中值得普及推广。

[关键词]复合维生素B;口腔溃疡;维生素B6

[中图分类号] R781.5     [文献标识码] A     [文章编号] 1674-4721（2019）9（b）-0131-03

Clinical effect of Multivitamin B in the treatment of oral ulcer

MEI Fang

Department of Stomatology， the Third Affiliated Hospital of Gannan Medical College， Jiangxi Province， Ganzhou   341000， China

[Abstract] Objective To observe the application effect of multivitamin B in the treatment of oral ulcer. Methods A total of 80 patients with oral ulcers admitted to our hospital from June 2018 to June 2019 were selected as research subjects. According to the outpatient date， there were divided into the study group and the control group， 40 cases in each group. The study group used Multivitamin B， and the control group used Vitamin B6， the therapeutic effects of the two groups was compared. Results The total effective rate of the study group was 97.5%， which was much higher than 82.5% of the control group， the difference was statistically significant （P<0.05）. The VAS pain score of the study group was lower than that of the control group， the time of symptom disappearance and the total treatment time of the study group were shorter than those of the control group， and the difference was statistically significant （P<0.05）. Conclusion Multivitamin B plays an important role in the treatment of oral ulcers， which can promote the healing of ulcers， shorten the treatment time， and alleviate the symptoms and pain as soon as possible. It is worthy of popularization in clinical practice.

[Key words] Multivitamin B; Oral ulcer; Vitamin B6

在临床中，口腔溃疡是常见的口腔疾病，常发生于舌缘、颊、唇等黏膜上。目前，本病尚無明确的病因，常认为与感冒、精神紧张、消化不良、维生素缺乏等有着一定关系[1]。当机体缺乏维生素、叶酸、微量元素时，身体免疫力会降低，进而提高了口腔溃疡的发生[2]。口腔溃疡属于自限性疾病，一般10 d便可自愈，不过有着复发性和周期性。另外，口腔溃疡的产生反映着机体有着潜在系统性疾病，如自主神经功能紊乱、维生素B族吸收障碍、肝炎、肠炎、胃溃疡等[3]。临床上，本病常采用对症治疗，以提升免疫力、消除病因，在药物选择方面一般会使用促进溃疡愈合、镇痛、消炎的药物，常用药物有复合维生素B、冰硼散、抗生素等，既有局部给药，也有口服用药，能有效改善溃疡引起的疼痛[4-5]，特别是复合维生素B，其属于人体必需的营养化合物。本研究旨在进一步明确复合维生素B在口腔溃疡治疗中的作用，现报道如下。

1资料与方法

1.1一般资料

选取2018年6月～2019年6月我院收治的80例口腔溃疡患者作为研究对象，依据门诊就诊日期单双号分为研究组与对照组，每组各40例。……