曲美他嗪联合琥珀酸美托洛尔治疗冠心病心力衰竭患者的临床疗效观察

张能

【摘要】目的 分析曲美他嗪联合琥珀酸美托洛尔治疗冠心病心力衰竭患者的临床疗效。方法 将2017年12月～2018年12月本院接收的50例冠心病心力衰竭患者，分组方法是随机化法，分为参照组、试验组，两组患者均接受常规药物治疗，利用血管紧张素转化酶抑制剂、利尿剂、洋地黄类制剂、血管紧张素Ⅱ受体阻滞剂等方式稳定患者病情，参照组在常规药物治疗基础之上给予琥珀酸美托洛尔治疗，试验组在参照组基础之上给予曲美他嗪进行治疗，然后对比两组患者治疗后的临床有效率。结果 药物干预后，试验组临床治疗总有效率（94%）明显更高，对比参照组数据（76%），差异有统计学意义（P<0.05）。结论 冠心病心力衰竭开展曲美他嗪联合琥珀酸美托洛尔治疗，可以促进患者病情明显改善，提高临床治疗的效果，值得研究推广。

【关键词】曲美他嗪;琥珀酸美托洛尔;冠心病;心力衰竭

【中图分类号】R969.4 【文献标识码】A 【文章编号】ISSN.2095.6681.2020.6..02

【Abstract】Objective   To analyze the clinical efficacy of trimetazidine combined with metoprolol succinate in the treatment of patients with coronary heart disease and heart failure.METHODS   Will in December 2017 to December 2018 in our hospital during the period of receiving of 50 patients with coronary heart disease， heart failure， grouping method is randomized method， divided into control group and experimental group，two groups of patients were treated with conventional drugs，the use of angiotensin converting enzyme inhibitors，diuretics，digitalis agents， angiotensin Ⅱ receptor blockers in patients with stable condition，the control group on the basis of routine drug treatment to succinic acid metoprolol therapy，patients in the control group based on the given trimetazidine treatment，and then compared the two groups after treatment in patients with clinical effectiveness.Results   After drug intervention，the total clinical response rate （94%） of the experimental group was significantly higher， which was statistically significant compared with the data of the control group （76%） （P<0.05）. Conclusion   The treatment of CHD heart failure with trimetazidine combined with metoprolol succinate can significantly improve the patient's condition and improve the clinical treatment effect，which is worthy of research and promotion.

【Key words】Trimetazidine;Metoprolol succinate;Coronary heart disease;Heart failure

心力衰竭属于心脏病症终末期的表现，是引发冠心病患者心源性猝死的重要因素，不仅会影响患者的各项身体指标，导致患者身心不健康，还会严重威胁患者生命安全，基于此，临床应积极应对冠心病患者心力衰竭的病症，以此及时挽救患者的生命[1]。本研究针对冠心病心力衰竭的治疗方式进行探讨，分析曲美他嗪联合琥珀酸美托洛尔在冠心病心力衰竭患者临床治疗方面的应用效果，现报告如下。

1 资料与方法

1.1  一般资料

将2017年12月～2018年12月本院接收……