贝那普利和阿托伐他汀联用对2型糖尿病并发肾病的治疗疗效分析

罗红春

[摘要] 目的 研究貝那普利和阿托伐他汀联用对于2型糖尿病并发肾病的治疗效果以及临床疗效。 方法 选取我院接收的100例2型糖尿病并发肾病患者，该次实验研究的时间范围为2018年8月—2019年8月，采用随机数字表法将这些患者分为实验组与对照组，其中实验组患者50例，对照组患者50例，实验组患者采用贝那普利和阿托伐他汀联用进行治疗，对照组患者采用常规的贝那普利进行治疗，比较两组患者的治疗效果、治疗满意度、以及两组患者治疗前后的24 h尿袋标定量、血肌酐、尿素氮以及尿蛋白排泄率等血脂指标以及观察指标。 结果 ①实验组患者的治疗效果优于对照组患者，组间差异有统计学意义（P<0.05）。②实验组患者的治疗满意度高于对照组患者，两组患者的治疗满意情况差异有统计学意义（P<0.05）。③实验组患者的血脂指标以及观察指标优于对照组患者，两组之间的数据差异有统计学意义（P<0.05）。 结论 贝那普利和阿托伐他汀联用效果良好，可以有效的对2型糖尿病进行治疗，有效地改善患者的血脂指标以及观察指标，提高患者的治疗满意度。

[关键词] 贝那普利;阿托伐他汀;2型糖尿病;肾病;治疗效果

[中图分类号] R587.1          [文献标识码] A          [文章编号] 1672-4062（2020）05（b）-0175-03

Analysis of the Efficacy of Benazepril Combined with Atorvastatin in the Treatment of Type 2 Diabetes with Nephropathy

LUO Hong-chun

Hemodialysis Room， Department of Nephrology， Simao District People's Hospital， Pu'er， Yunnan Province， 665000 China

[Abstract] Objective To study the therapeutic effect and clinical efficacy of benazepril combined with atorvastatin on type 2 diabetes mellitus with nephropathy. Methods 100 patients with type 2 diabetes complicated with kidney disease received in the hospital were selected. The time range of this experimental study was from August， 2018 to August， 2019. These patients were divided into experimental group and control group by random number table method. Compared with the control group， including 50 patients in the experimental group and 50 patients in the control group， the patients in the experimental group were treated with benazepril and atorvastatin， and the patients in the control group were treated with conventional benazepril. Patients' treatment effects， treatment satisfaction， and 24-hour urine bag standardization， blood creatinine， urea nitrogen， and urine protein excretion rate before and after treatment in two groups of patients， as well as observation indicators. Results 1.The treatment effect of the experimental group was better than that of the control group， and there were differences between the groups （P<0.05）. 2.The treatment satisfaction of the experimental group was higher than that of the control group. There was a difference in the treatment satisfaction between the two groups and the difference was statistically significant （P<0.05）. 3.The blood lipid index and observation index of patients in the experimental group were better than those in the control group. The data between the two groups were different and the difference was statistically significant （P<0.05）. Conclusion The combination of benazepril and atorvastatin has a good effect， which can effectively treat type 2 diabetes， effectively improve the blood lipid index and observation index of patients， and improve the patient's treatment satisfaction. It is worth further promotion and application in clinical treatment.

[Key words] Benazepril; Atorvastatin; Type 2 diabetes; Kidney disease; Treatment effect

2型糖尿病是糖尿病的常见类型，该疾病具有极高发病率和致残率，若治疗不及时，严重影响患者生活质量，且对其预后造成影响。近些年来伴随着我们国家的社会经济的不断发展与进步，糖尿病的发病几率正在逐年提升，截止至2007年，我们国家已经成为了世界上的第二大糖尿病国家，患者共有4000余万人，患病率达到了4.5%。肾病是糖尿病这一疾病的重要并发症之一，如果不及时的对该疾病进行治疗，将有可能导致患者的生命安全受到威胁[1～4]。该疾病往往是多发性的，该疾病的发病因素与患者的各项因素相关，对于该疾病的治疗一方面需要有效控制患者的病情，另一方面则需要尽量地改善患者的血糖水平，為此有效探讨该疾病的治疗方法是必要的。……