舒利迭联合无创通气对老年慢性阻塞性肺疾病急性加重期并Ⅱ型呼吸衰竭的疗效分析

董巍

[摘要] 目的 探究舒利迭联合无创通气对老年慢性阻塞性肺疾病急性加重期并Ⅱ型呼吸衰竭的疗效。方法 方便选取该院2017年5月—2019年1月期间诊治的118例老年慢性阻塞性肺疾病急性加重期并Ⅱ型呼吸衰竭患者进行病情分析。取得患者及家属同意后，按照入院顺序将其平均分成观察组、对照组，每组59例患者。对照组患者在治疗期间选用常规治疗方法，观察组患者在治疗期间选用舒利迭联合无创通气治疗方法。结果 治疗前，观察组患者峰值呼气流速、第1秒用力呼吸容积与用力肺活量与对照组患者差异无统计学意义（P>0.05）;治疗后，观察组患者肺功能情况显著优于对照组患者，差异有统计学意义（P<0.05）;观察组与对照组患者治疗有效率分别为98.35%、84.7%（χ2=5.347，P=0.014）;观察组与对照组患者住院天数分别为（17.1±1.6）d、（25.3±2.9）d，差异有统计学意义（t=2.354，P=0.025）。结论 舒利迭联合无创通气既能够有效改善老年慢性阻塞性肺疾病急性加重期并Ⅱ型呼吸衰竭患者的肺部功能情况，还能减少住院天数，治疗效果极佳，应推广使用。

[关键词] 舒利迭;无创通气;老年;慢性阻塞性肺疾病急性加重期;Ⅱ型呼吸衰竭

[Abstract] Objective To investigate the efficacy of sulidate combined with non-invasive ventilation in the acute exacerbation of chronic obstructive pulmonary disease in the elderly with type Ⅱ respiratory failure. Methods A total of 118 elderly patients with chronic obstructive pulmonary disease with acute exacerbation and type Ⅱ respiratory failure diagnosed and treated during May 2017-January 2019 were analyzed. After obtaining the consent of the patients and their families， they were evenly divided into observation group and control group according to the order of admission， with 59 patients in each group. Patients in the control group were convenient treated with conventional treatment during the treatment period， and patients in the observation group were treated with Sulidie and noninvasive ventilation during the treatment period. Results There was no significant difference in peak expiratory flow rate， first second forced breathing volume and forced vital capacity between the observation group and the control group （χ2=5.014， P=0.095）. After treatment， the pulmonary function in the observation group was significantly better than that in the control group（P<0.05）. Total effective rate of treatment in observation group and control group（98.3%，84.7%），（χ5.347，P=0.014）. The hospitalization days of patients in the observation group and control group were （17.1±1.6） d、（25 .3±2.9） d， the differences were statistically significant（t=2.354，P=0.025）. Conclusion Sulidie combined with non-invasive ventilation can not only effectively improve the pulmonary function of elderly patients with chronic obstructive pulmonary disease with acute exacerbation and type Ⅱ respiratory failure， but also reduce the length of hospital stay.

[Key words] Shulidie;Non-invasive ventilation; Eldety Acute exacerbation of chronic obstructive pulmonary disease; Type Ⅱ respiratory failure

慢性阻塞性肺疾病是較为常见的中老年病症，该病具有发病率高、致残率高、病死率高的特点，对患者身体健康及生活质量有非常消极的影响[1-2]。老年慢性阻塞性肺疾病患者极易患有呼吸衰竭并发症，如果患者的病情没有进行及时有效的治疗，会直接危及生命安全[3-4]。为了提升老年慢性阻塞性肺疾病急性加重期并Ⅱ型呼吸衰竭患者的治疗有效率，将该院2017年5月—2019年1月期间诊治的118例患者给予不同方法进行治疗，报道如下。

1  资料与方法

1.1  一般资料

方便选取该院诊治的118例老年慢性阻塞性肺疾病急性加重期并Ⅱ型呼吸衰竭患者平均分成观察组、对照组，每组59例患者。观察组有30例男性患者、29例女性患者;患者年龄58～75岁，平均年龄（65.74±2.31）岁。对……