伴糖尿病及不伴糖尿病的口腔颌面多间隙感染患者的临床特征及治疗效果

周强

[摘要] 目的 对比口腔颌面多间隙感染患者中伴糖尿病及不伴糖尿病的临床特征及治疗效果情况。方法 方便选取60例在该院接受治疗的口腔颌面多间隙感染患者作为临床研究对象，入院时间为2011年8月—2018年8月，根据是否伴糖尿病进行分组，其中40例患者伴糖尿病，作为观察组，20例患者不伴糖尿病，作为对照组，比对临床特征及治疗效果情况。结果 观察组的平均受累间隙数显著高于对照组，差异有统计学意义（P<0.05）;两组患者的间隙分布位置无显著差异，差异无统计学意义（P>0.05）;观察组的平均切开引流切口数以及住院时间显著高于对照组，差异有统计学意义（P<0.05）;观察组并发症发生率显著高于对照组的（40.00%>10.00%），差异有统计学意义（χ2=5.714，P<0.05）。结论 口腔颌面多间隙感染患者中伴糖尿病者病情更为严重，且以间隙被感染的表现居多，并伴有诸多并发症，延长住院时间。

[关键词] 口腔颌面多间隙感染;糖尿病;临床特征;治疗效果

[Abstract] Objective To compare the clinical features and treatment effects of diabetes with and without diabetes in patients with multiple gap infections of the oral and maxillofacial region. Methods Sixty patients with oral and maxillofacial multi-gap infection treated in the hospital were convenient selected as clinical research subjects. The hospital admission time was from August 2011 to August 2018. They were grouped according to whether they were accompanied by diabetes， of which 40 patients were associated with diabetes as the observation group， 20 patients were not accompanied by diabetes as the control group， the clinical characteristics and treatment effects were compared. Results The average number of affected gaps in the observation group was statistically significantly higher than that in the control group， and the difference was statistically significant （P<0.05）. There was no significant difference in the gap distribution position between the two groups of patients， and the difference was not statistically significant （P>0.05）. The average number of incisions and drainage incisions and hospital stay were significantly higher than those in the control group， and the difference was statistically significant （P<0.05）; the incidence of complications in the observation group was significantly higher than that in the control group （40.00% > 10.00%）， and the difference was statistically significant （χ2=5.714， P<0.05）. Conclusion Among patients with oral and maxillofacial multi-gap infections， those with diabetes are more severe， and most of them are infected with gaps， and they are accompanied by many complications， which prolongs the length of hospitalization.

[Key words] Oral and maxillofacial multi-gap infection; Diabetes; Clinical features; Treatment effect

口腔頜面多间隙感染的发生与免疫功能与宿主血糖水平有较大关系，由于机体在高血糖水平下，中性粒细胞以及白细胞杀菌活性降低，补体激活功能以及细胞免疫功能紊乱，且糖尿病患者多免疫机制较弱，对细菌敏感度较高，感染性疾病发生率高，且与未伴有糖尿病的该疾病患者相比，患有糖尿病的该疾病患者感染发展速度也不同，预后较差[1-3]。说明了患者的临床特征会受到糖尿病的影响。现为深入探究口腔颌面多间隙感染患者中伴糖尿病及不伴糖尿病的临床特征及治疗效果情况，特方便选取2011年8月—2018年8月在该院进行治疗的60例该疾病患者为研究对象，收集相关资料，并进行分析，报道如下。

1  资料与方法

1.1  一般资料

方便选取60例在该院接受治疗的口腔颌面多间隙感染患者作为临床研究对象，根据是否伴糖尿病进行分组，其中40例患者伴糖尿病，作为观察组，20例患者不伴糖尿病，作为对照组。……