从脾论治脑卒中后抑郁研究进展

2020-08-10 09:15:45侯臻臻韩翔祁丽丽韩振翔
上海医药 2020年14期

侯臻臻 韩翔 祁丽丽 韩振翔

摘 要 脑卒中后抑郁是一种常见的神经精神症状,不仅会影响患者的康复和生活质量,而且对照顾者也有沉重的负担。脑卒中后抑郁的自杀率和死亡率比单纯脑卒中高许多,因此近几年引起高度重视。全文阐述脾在情志、气机与抑郁症的相关性,从而提出“脑脾相关”理论,为临床研究提供新的思路。

关键词 抑郁;脑卒中;脾

中图分类号:R743.3 文献标志码:A 文章编号:1006-1533(2020)14-0013-03

Research progress in the treatment of post-stroke depression from the perspective of spleen

HOU Zhenzhen1, HAN Xiang2, QI Lili3, HAN Zhenxiang1

(1. Rehabilitation Department of Neurology of the Seventh Peoples Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200120, China; 2. Internal Medicine-Neurology Department of Huashan Hospital affiliated to Fudan University, Shanghai 200040, China; 3. Emergency Medicine Department of Yueyang Integrated Traditional Chinese and Western Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200080, China)

ABSTRACT Post-stroke depression(PSD) is a common neuropsychiatric symptom that not only affects patientsrehabilitation and quality of life, but also places a heavy burden on caregivers. The suicide rate and mortality rate of PSD are much higher than that of stroke alone, so it has attracted much attention in recent years. The article expounds the relationship between the spleen in emotion, Qi and depression, and then puts forward the “brain-spleen correlation” theory to provide new ideas for clinical research.

KEY WORD depression; stroke; spleen

脑卒中后抑郁(post-stroke depression,PSD)是脑卒中后常见并发症,是脑卒中后常见的心理障碍,是一种以显著而持久的心境低落为主要临床特征的病症,同时伴有失眠、记忆缺失或饮食失调等症状,严重者可出现自杀念头和行为。PSD在脑卒中后的发病率占31%~38%[1],PSD的发生可导致治疗效率下降,功能恢复不佳,社会参与度下降,生活质量减退,并且增加脑卒中的死亡率和复发风险[2]。有研究表明脑卒中后患者无论在急性期或恢复期,抑郁与功能结局呈负相关,康复性训练依从性低,从而对患者生活质量产生不利影响[3]。不仅如此,临床发现脑卒中伴有抑郁症患者往往更易发展成为痴呆,从而带来沉重的经济负担与社会负担[4]。

PSD属于中医学“郁病”范畴,属七情之一,其发病与中风后经脉痹阻、脏腑阴阳失调有关。常见症状多表现为情绪不宁、胁肋胀满、悲忧善哭、胸部闷塞、腹胀、喜怒无常。然而,脾胃学说在情志的产生、活动中有着特殊的地位,对于深入探讨脾胃与抑郁症的相关性,具有重要的理论价值和临床指导意义。……

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