果桂散隔姜灸脐法对阳虚型老年便秘患者胃肠激素干预机制的研究

2020-08-15 13:23:36张敏王家兰万春平尹丽华方勇蕊杨国琳
云南中医中药杂志 2020年6期

张敏 王家兰 万春平 尹丽华 方勇蕊 杨国琳

摘要:目的 观察果桂散隔姜灸脐法对阳虚型老年便秘患者胃肠激素干预机制。方法 60例患者随机分为2组,每组30例。对照组采取艾条隔姜灸脐法进行治疗,观察组采取果桂散隔姜灸脐法进行治疗。2组均治疗1个疗程,观察治疗前后的胃肠激素水平、症状变化,并进行统计分析。结果 治疗后观察组的胃肠激素水平改善情况明显优于对照组,差异有统计学意义(P<0.05);观察组的总有效率93.33%明显高于对照组70.00%(P<0.05)。结论 果桂散隔姜灸脐法治疗阳虚型老年便秘患者的效果显著,其作用机制为通过调节胃肠激素介导。

关键词:阳虚型老年便秘;果桂散隔姜灸脐法;胃肠激素

中图分类号:R256.35 文献标志码:B 文章编号:1007-2349(2020)06-0045-03

Study on the Interventional Mechanism of Guogui Powder and Ginger Moxibustion on Gastrointestinal Hormones in Elderly Patients with Constipation due to Yang Deficiency

ZHANG Min, WANG Jialan, WAN Chun-ping, YIN Li-hua, FANG Yong-rui, YANG Guo-lin

(Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming 650021, China)

【Abstract】Objective: To study the intervention mechanism of Guogui powder and ginger moxibustion on the gastrointestinal hormones in elderly patients with constipation due to yang deficiency. Methods: 60 patients were randomly divided into two groups, 30 cases per group. The control group was treated with moxa sticks with ginger moxibustion navel method and the observation group was treated with Guogui powder with moxibustion and umbilical moxibustion. Both groups were treated for one course of treatment. The changes of gastrointestinal hormone levels and symptoms before and after treatment were observed and statistically analyzed. Results: After treatment, the gastrointestinal hormone level of the observation group was significantly better than that of the control group, and the difference was statistically significant (P<0.05). The total effective rate of the observation group was 93.33%, which was significantly higher than that (70.00%) of the control group (P<0.05). Conclusion: Guogui powder and ginger moxibustion umbilical method is effective in treating elderly patients with constipation due to yang deficiency type. Its mechanism is mediated by regulating gastrointestinal hormones.

【Key words】elderly patients with constipation due to yang deficiency, Guogui powder and ginger moxibustion umbilical method, gastrointestinal hormone

便秘是一種常见的消化系统疾病,临床症状为大便干结、排便无力、排便不畅及排便周期延长等,老年人是便秘是的高发人群,易增加胃肠道疾病的发病率,对老年人正常生活造成严重的影响[1]。阳虚型便秘是一种常见的老年便秘证型,中医治疗老年性便秘疗效显著,果桂散隔姜灸脐法可用于治疗阳虚型老年便秘。研究显示,阳虚型便秘与胃肠激素的分泌水平具有密切关系[2]。同时探讨果桂散隔姜灸脐法对阳虚型老年便秘患者胃肠激素干预机制。

1 资料与方法

1.1 一般资料 本研究方案已通过云南省中医医院伦理委员会的批准。60例老年阳虚便秘患者均为2018年1月—2018年10月在本科门诊及住院治疗患者,采用半随机入组法按住院单双号顺序分为对照组(单号)与观察组(双号)各30例。观察组患者中,男13例,女17例;年龄为60~90岁,平均(70.25±6.24)岁;病程1年~6年,平均(2.52±0.78)年。对照组患者中,男14例,女16例;年龄为61~90岁,平均(70.53±6.31)岁;病程1年~6年,平均(2.55±0.79)年。……

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