支气管肺炎患儿的抗生素治疗效果分析

栾伟

【摘要】 目的：研究分析对支气管肺炎患儿行大环内酯类抗生素治疗的临床效果。方法：选取2018年1-12月在笔者所在医院就诊的100例支气管肺炎患儿作为研究对象，将其随机分为对照组和观察组，每组50例，对照组行红霉素治疗干預，观察组行阿奇霉素序贯法干预，对比两组治疗总有效率、不良反应发生率、患儿家属满意度及患儿症状缓解时间。结果：观察组治疗总有效率高于对照组，不良反应发生率低于对照组，差异均有统计学意义（P<0.05）;观察组家属满意度高于对照组，差异有统计学意义（P<0.05）;观察组退热时间、咳嗽缓解时间、啰音消失时间和呼吸不畅缓解时间均早于对照组，差异均有统计学意义（P<0.05）。结论：在支气管肺炎患儿的治疗过程中，阿奇霉素序贯法治疗效果优于红霉素，有利于降低患儿不良反应发生率，提高治疗总有效率和患儿家属满意度，加速缓解临床症状，是一种有效的治疗方式，值得大力推广。

【关键词】 支气管肺炎患儿 大环内酯类 红霉素 阿奇霉素 临床效果

doi：10.14033/j.cnki.cfmr.2020.20.068 文献标识码 B 文章编号 1674-6805（2020）20-0-03

Effect of Antibiotic Treatment on Children with Bronchopneumonia/LUAN Wei. //Chinese and Foreign Medical Research， 2020， 18（20）： 163-165

[Abstract] Objective： To study and analyze the clinical effect of macrolide antibiotics on children with bronchopneumonia. Method： A total of 100 children with bronchopneumonia treated in our hospital from January to December 2018 were selected as the objects of this study. They were randomly divided into the control group and the observation group， 50 cases in each group. The control group received Erythromycin treatment intervention， the observation group received Azithromycin sequential intervention. The total effective rate of treatment， the incidence of adverse reactions， the satisfaction of family members and the remission time of symptoms were compared between the two groups. Result： The total effective rate of treatment in the observation group was higher than that in the control group， and the incidence of adverse reactions was lower than that in the control group， the differences were statistically significant （P<0.05）. The satisfaction of family members in the observation group was higher than that in the control group， the difference was statistically significant （P<0.05）. The antifebrile time， cough relief time， rales disappear time and dyspnea relief time of in the observation group were earlier than those in the control group， the differences were statistically significant （P<0.05）. Conclusion： In the treatment of children with bronchopneumonia， Azithromycin sequential therapy is more effective than erythromycin， which is beneficial to reduce the incidence of adverse reactions in children， improve the total effective rate of treatment and satisfaction with the families of children， and accelerate the remission of clinical symptoms. It is an effective treatment method and is worth promoting

[Key words] Bronchial pneumonia in children Macrolides Erythromycin Azithromycin Clinical effect

First-authors address： Yunmeng Traditional Chinese Medicine Hospital， Yunmeng 432500， China

支气管肺炎是一种常见的呼吸道疾病，儿童属于此病的高发群体，且患此病的人数呈逐年增多趋势。支气管肺炎伴有诸多临床症状，其中以发热、呼吸不畅、多系统功能衰竭和刺激性干咳为主，不仅对患儿的生活质量会造成严重负面影响，抗生素治疗的高额费用也会为其家庭带来沉重的治疗负担。据资料显示，诱发支气管肺炎的主要因素是因为感染流感嗜血杆菌和肺炎链球菌、营养匮乏、低体重初生儿等，且主要发病时期为春冬季节。因此，要获得较好的治疗效果，需要行抗生素治疗干预，且抗生素也是治疗支气管肺炎的主要药物[1]。此次选取2018年1-12月在笔者所在医院就诊的支气管肺炎患儿100例作为研究对象，对其行大环内酯类抗生素治疗，观察其临床效果，具体报道如下文所示。

1 资料与方法

1.1 一般资料

选取2018年1-12月在笔者所在医院就诊的支气管肺炎患儿100例。……