经尿道前列腺电切术后发生尿路感染的危险因素

宋静 张玲玲 陈蕾 王洋

[摘要]目的 探討经尿道前列腺电切术后发生尿路感染的危险因素。方法 选取2018年1月～2019年2月我院收治的200例经尿道前列腺电切术患者作为研究对象，按照术后有无尿路感染的方法分为观察组（100例）与对照组（100例），观察组患者伴有尿路感染，对照组患者无尿路感染。分析经尿道前列腺电切术后发生尿路感染的危险因素。结果 两组患者的年龄≥70岁、手术时间>1 h、导尿管留置时间>5 d、术前未预防使用抗生素比较，差异有统计学意义（P<0.05）。以年龄≥70岁、手术时间>1 h、导尿管留置时间>5 d、术前未预防使用抗生素为自变量，以术后发生尿路感染为因变量进行Logistic回归分析，结果显示，年龄≥70岁、手术时间>1 h、导尿管留置时间>5 d、术前未预防使用抗生素为经尿道前列腺电切术患者发生尿路感染的危险因素（P<0.05）。结论 经尿道前列腺电切术后发生尿路感染的危险因素包括年龄≥70岁、手术时间>1 h、导尿管留置时间>5 d、术前未预防使用抗生素，应早期实施预防措施。

[关键词]经尿道前列腺电切;尿路感染;危险因素

[中图分类号] R699.8          [文献标识码] A          [文章编号] 1674-4721（2020）7（a）-0098-03

Risk factors of urinary tract infection after transurethral resection of prostate

SONG Jing1   ZHANG Ling-ling1   CHEN Lei1   WANG Yang2▲

1. Department of Urology， Hongqi Hospital Affiliated to Mudanjiang Medical University， Heilongjiang Province， Mudanjiang   157000， China; 2. Operating Room， Hongqi Hospital Affiliated to Mudanjiang Medical University， Heilongjiang Province， Mudanjiang   157000， China

[Abstract] Objective To investigate the risk factors of urinary tract infection after transurethral resection of prostate. Methods A total of 200 cases of transurethral resection of prostate admitted to our hospital from January 2018 to February 2019 were selected as the study objects. According to the methods of postoperative urinary tract infection or not， they were divided into the observation group （100 cases） and the control group （100 cases）. The observation group was accompanied by urinary tract infection， while the control group was free of urinary tract infection. The risk factors of urinary tract infection after transurethral prostatectomy was analyzed. Results There were statistically significant differences between the two groups of patients in age ≥70 years， operation time >1 h， indwelling catheter time >5 d， and preoperative preventive use of antibiotics without prevention （P<0.05）. Taken age ≥70 years， operation time >1 h， indwelling catheter time >5 d， and preoperative not preventive use of antibiotics as independent variables， postoperative urinary tract infection as the dependent variable， Logistic regression analysis was conducted. According to the results， age ≥70 years， operation time >1 h， indwelling catheter time >5 d， and preoperative preventive use of antibiotics for the urethra prostate electricity cut method in patients were risk factors for urinary tract infection （P<0.05）. Conclusion The risk factors for urinary tract infection after transurethral prostatectomy include age ≥70 years， operation time >1 h， indwelling catheter time >5 d， and preoperative not preventive use of antibiotics， and early reventive measures should be taken.

[Key words] Transurethral resection of prostate; Urinary tract infection; Risk factors

研究显示，良性前列腺增生发病率不断增加，有关良性前列腺增生的发病机制研究较多，但病因至今仍未能阐明，可能是由于上皮和间质细胞增殖和细胞凋亡的平衡遭到破坏，其他相关因素与雌激素的相互作用、前列腺间质与腺上皮细胞的相互作用、生长因子、炎症细胞、神经递质及遗传因素等，随着患者年龄的不断增长，其下尿路症状也不断加重，因此对于该类患者实施一项有效的治疗方式十分重要[1]。对于该类患者常实施手术治疗，经尿道前列腺……