芪蓉润肠口服液治疗老年慢性便秘的效果探究

张燕玲 袁兵源 周志聪

【摘要】 目的 探討在治疗老年慢性便秘中使用芪蓉润肠口服液的临床效果。方法 82例老年慢性便秘患者， 根据治疗方法不同分为观察组与对照组， 各41例。对照组患者采用乳果糖口服溶液治疗， 观察组患者采用芪蓉润肠口服液治疗。比较两组治疗前后排便次数、两组不良反应发生率、两组药物费用。结果 治疗前， 两组排便次数比较差异无统计学意义（P>0.05）;治疗后， 两组排便次数均有所增多， 且观察组（7.36±2.94）次/周多于对照组（5.39±1.15）次/周， 差异有统计学意义（P<0.05）。观察组不良反应发生率为0， 低于对照组的9.76%（4/41）， 差异有统计学意义（χ2=4.205， P<0.05）。观察组的药物费用为（1072.58±151.37）元， 低于对照组的（1664.87±164.21）元， 差异有统计学意义（χ2=16.981， P<0.05）。结论 使用芪蓉润肠口服液治疗老年慢性便秘具有显著的临床效果， 可有效改善患者临床症状， 增加其每周排便次数， 而且还具有较高的安全性， 可减少不良反应的发生， 同时价格实惠， 值得临床大力推广。

【关键词】 芪蓉润肠口服液;乳果糖口服溶液;老年慢性便秘;排便次数;安全性

DOI：10.14163/j.cnki.11-5547/r.2020.24.046

【Abstract】 Objective   To discuss the clinical effect of Qirong Runchang oral liquid in the treatment of chronic constipation in the elderly. Methods   A total of 82 elderly patients with chronic constipation were divided into observation group and control group by different treatment methods， with 41 cases in each group. The control group was treated by lactulose oral solution， and the observation group was treated by Qirong Runchang oral liquid. The frequency of defecation before and after treatment， incidence of adverse reactions and drug costs were compared between the two groups. Results   Before treatment， there was no statistically significant difference in frequency of defecation between the two groups （P>0.05）. After treatment， the frequency of defecation increased in both groups， and the observation group （7.36±2.94） times/week was more than that of the control group （5.39±1.15） times/week， and the difference was statistically significant （P<0.05）. The incidence of adverse reactions of the observation group was 0， which was lower than that of the control group 9.76%（4/41）， and the difference was statistically significant （χ2=4.205， P<0.05）. The drug costs of the observation group was （1072.58±151.37） yuan， which was lower than that of the control group （1664.87±164.21） yuan， and the difference was statistically significant （χ2=16.981， P<0.05）. Conclusion   Qirong Runchang oral liquid has significant clinical effects on chronic constipation in the elderly， which can not only effectively improve the clinical symptoms of patients， increase the frequency of defecations per week with high safety， but also reduce the occurrence of adverse reactions and is affordable. It is worthy of clinical promotion.

【Key words】 Qirong Runchang oral liquid; Lactulose oral solution; Chronic constipation in the elderly; Defecation times; Safety

慢性便秘是一种发病率较高的长时期反复便秘而引起大便秘结不通的慢性肠胃疾病， 可发生于各个年龄段， 但老年人为高发群体[1]。该疾病主要发病原因为老年人的脏器功能产生生理性衰退、肠道蠕动能力下降、直肠肌和腹肌产生萎缩以及活动量的减少， 老年慢性便秘以排便次数减少和排便困难为主要症状[2]。长期便秘的老年人可因肠道内毒素吸收过多而产生头晕、食欲不振及失眠等症状， 严重便秘可增加其患上各类型疝的可能性和结肠癌， 由于排便困难且时间长， 由蹲位站起身时， 极有可能会因为体位性低血压引起脑供血不足发生晕厥而摔倒， 对患者的生命健康和安全造成严重威胁。目前， 医学上治疗该病的主要方法有一般治疗和药物治疗， 一般治疗指的是饮食疗法， 药物主要有乳果糖口服溶液、芪蓉润肠口服液等。本研……