杜智超
【摘 要】目的:研究琥珀酸美托洛尔缓释片联合曲美他嗪治疗冠心病心绞痛的临床价值。方法:入组74例冠心病心绞痛患者,均为本院2019年1月-2019年12月收治入院。按照电脑随机分组,对比组和研究组各37例。对比组给予常规治疗,研究组联合琥珀酸美托洛尔缓释片和曲美他嗪治疗。对比两组治疗效果。结果:用药有效率对比,研究组为94.59%,对比组为81.08%,研究组更高(P<0.05)。研究组心绞痛发作次数、持续时间以及硝酸甘油减少比例、不良反应发生率均优于对比组(P<0.05)。结论:将琥珀酸美托洛尔缓释片和曲美他嗪用于冠心病心绞痛的治疗中,效果明显。
【关键词】冠心病;心绞痛 ;琥珀酸美托洛尔缓释片;曲美他嗪
【中图分类号】R541 【文献标识码】A 【文章编号】1672-3783(2020)06-0060-02
【Abstract】Objective:To study the clinical value of metoprolol succinate sustained release tablets combined with trimetazidine in the treatment of angina pectoris. Methods:74 patients with angina pectoris were admitted from January 2019 to December 2019. According to the computer, 37 cases were randomly divided into the control group and the study group. The control group was given conventional treatment, and the study group was treated with metoprolol succinate sustained-release tablets and trimetazidine. The therapeutic effects of the two groups were compared. Results:the effective rate was 94.59% in the study group and 81.08% in the control group, higher in the study group (P < 0.05). The times and duration of angina pectoris, the proportion of reducing nitroglycerin and the incidence of adverse reactions in the study group were better than those in the control group (P < 0.05). Conclusion:metoprolol succinate and trimetazidine are effective in the treatment of angina pectoris.
【Key words】coronary heart disease; angina pectoris; metoprolol succinate sustained release tablets; Trimetazidine
冠心病心絞痛是临床多发疾病,与冠状动脉供血不足导致的心肌缺氧以及缺血有关[1]。不稳定型心绞痛是冠心病的一种常见分型。该疾病有进一步引发心梗的可能,甚至造成了极高的临床死亡率[2]。临床采用阿司匹林等进行治疗,远期效果不理想。为了对冠心病心绞痛的治疗方法进行深入研究,本课题将琥珀酸美托洛尔缓释片联合曲美他嗪应用于冠心病心绞痛的对比治疗,现报道如下。
1 资料与方法
1.1 一般资料
入组74例冠心病心绞痛患者,均为本院2019年1月-2019年12月收治入院。按照电脑随机分组,对比组和研究组各37例。研究组,男、女各20例和17例,年龄52-75岁,均值(62.65±2.16)岁。病程0.5-7年,平均(3.45±0.77)年。对比组,男、女各21例和16例,年龄51-76岁,均值(62.88±3.02)岁。病程0.4-7年,平均(3.65±0.65)年。入选标准:(1)患者静息心率在60次/分钟以上,经临床与动脉造影等检查,确诊为冠心病心绞痛;(2)发病时意识清醒;排除标准:(1)合并严重呼吸系统疾病;(2肝肾功能损伤或者其他心脑血管疾病患者。……