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【摘要】目的:探讨分化型甲状腺癌患者在行手术治疗后选用碘131进行治疗的价值。方法:选86例分化型甲状腺癌患者研究,按1:1比例分为对照组(n=43,选用促甲状腺素治疗)、观察组(n=43,选用碘131治疗),统计两组临床疗效、生存率。结果:观察组临床疗效(93.02%)高于对照组(76.74%),统计值χ2=4.4405, P<0.05。观察组生存率(1年88.37%、2年 53.49%、3年32.56%)高于对照组(1年46.61%、2年23.26%、3年 11.63%),统计值 P<0.05。结论:碘 131在手术后分化型甲状腺癌治疗中效果确切,可改善甲状腺水平,亦可提高其远期、近期生存率,值得借鉴。
【关键词】手术治疗;分化型甲状腺癌;碘131;生存率
[中图分类号]R736.1[文献标识码]A[文章编号]2096-5249(2021)21-0076-01
Objective toAnalyze the Effect ofIodine 131 in the Treatment ofDifferentiated Thyroid CancerAfter Operation
CHANG Yao-yao(Department of Nuclear Medicine, Shengli Oilfield Central Hospital, Dongying Shandong 257000, China)
[Abstract] Objective: To explore the value of iodine-131 therapy for patients with differentiated thyroid cancer after surgery. Methods:86 patients with differentiated thyroid cancer were divided into control group (n =43, treated with thyrotropin) and observation group (n =43, treated with iodine 131) according to the ratio of 1:1. The clinical efficacy and survival rate of the two groups were analyzed. Result: The clinical efficacy of observation group(93.02%)was higher than that of control group(76.74%), statistical value=4.4405, P<0.05. The survival rate of the observation group(1 year 88.37%, 2 years 53.49%, 3 years 32.56%)was higher than the control group(1 year 46.61%, 2 years 23.26%, 3 years 11.63%), the statistical value P<0.05. Conclusion: Iodine 131 has a definite effect in the treatment of differentiated thyroid cancer after surgery. It can improve the level of thyroid and increase its long-term and short-term survival rate. It is worth learning.
[Key words] Surgical Treatment; Differentiated Thyroid Cancer; Iodine 131; Survival Rate
甲狀腺癌是起源于甲状腺滤泡上皮的恶性肿瘤,以无痛性颈部肿块、结节为临床表现,据统计近年甲状腺癌以每年20%的速度增长,为威胁患者生存质量的常见头颈部肿瘤[1]。分化型甲状腺癌(Ⅳ期)存在易转移、生存时间短等特点,手术为治疗该病主要方案,但甲状腺全切除治疗后依旧残留部分甲状腺组织,为提高远期、近期生存率临床建议术后展开碘131或促甲状腺素治疗,有报告指出手术治疗后选择碘131可延长患者生存时间,为明确其具体治疗价值,本文选择2018.02~2020.02区间接收分化型甲状腺癌患者86例研究,汇总如下。
1 资料与方法
1.1一般资料纳入86例分化型甲状腺癌患者均选自2018.02~2020.02区间,按1: 1比例分为2组。观察组43例中男/女=23/20,年龄均值(45.92±7.91)岁;13例乳头状癌、20例滤泡状癌、10例混合型癌。对照组43例中男/女=22/21,年龄均值
(45.88±7.73)岁;14例乳头状癌、18例滤泡状癌、11例混合型癌,数据统计P>0.05。
1.2方法 (1)对照组……