保乳手术联合辅助化疗治疗乳腺癌的安全性及对乳房美容效果的影响分析

[摘要]目的：探究分析保乳手術（Breast-conserving surgery，BCS）联合辅助化疗治疗乳腺癌的安全性及对乳房美容效果的影响。方法：选择2017年2月-2019年2月于笔者医院接受治疗的124例乳腺癌患者，并采用随机数字表法分为两组。其中对照组62例采用乳腺癌改良根治术治疗，观察组62例采用BCS联合辅助化疗治疗。治疗后对比两组治疗效果与乳房美容效果、生活质量以及并发症与复发情况。结果：观察组治疗后乳房美容优良率为96.77%显著高于对照组的75.81%，差异有统计学意义（P<0.05）。观察组术后生理状况、心理状况、功能状况、家庭/社会状况、附加条目以及生活质量总评分均显著高于对照组，差异有统计学意义（P<0.05）。观察组术后并发症发生率为3.23%显著低于对照组的12.90%，差异有统计学意义（P<0.05）。两组局部复发率比较差异无统计学意义（P>0.05）。结论：BCS联合辅助化疗治疗乳腺癌安全性较高，乳房美容效果显著，可有效控制并发症的发生，改善患者生活质量，疗效确切，值得临床推广采用。

[关键词]保乳手术;辅助化疗;乳腺癌;改良根治术;安全性;美容效果

[中图分类号]R737.9    [文献标志码]A    [文章编号]1008-6455（2021）03-0070-03

Safety Analysis of Breast-conserving Surgery Combined with Adjuvant Chemotherapy in the Treatment of Breast Cancer and its Effect on Cosmetic

Effect of Breast

CAI Yi

（Department of Galactophore，the First Affiliated Hospital of Hunan Traditional Chinese Medical College，Zhuzhou 412000，Hunan，China）

Abstract： Objective  To explore and analyze the safety analysis of breast-conserving surgery combined with adjuvant chemotherapy for breast cancer and its influence on the cosmetic effect of breast. Methods  124 cases of breast cancer patients treated in our hospital from February 2017 to February 2019 were selected and divided into two groups by random number table method. Among them， 62 patients in the control group were treated with modified radical mastectomy， and 62 patients in the observation group were treated with BCS combined with adjuvant chemotherapy. After treatment， the treatment effect， cosmetic effect， quality of life， complications and disease recurrence were compared between the two groups. Results  The excellent and good rate of breast beauty in the observation group was 96.77% significantly higher than that in the control group（75.81%）， the difference was statistically significant（P<0.05）. Postoperative physiological status， psychological status， functional status， family/social status， additional items and total quality of life scores of the observation group were significantly higher than those of the control group（P<0.05）. The postoperative complication rate of the observation group was 3.23%， which was significantly lower than that of the control group（12.90%， P<0.05）. There was no statistical difference in local recurrence rate between the two groups （P>0.05）. Conclusion  BCS combined with adjuvant chemotherapy in the treatment of breast cancer has a higher safety， significant cosmetic effect， can effectively control the occurrence of complications， improve the quality of life of patients， the curative effect is exact， and is worthy of clinical promotion.

Key words： breast-conserving surgery; adjuvant chemotherapy; breast cancer; modified radical mastectomy; safety; cosmetic effect

流行学调查表明，全球范围内乳腺癌发病率是仅次于肺癌的第二大恶性肿瘤。由于地理位置、种族的不同也会导致乳腺癌临床特征、发病率有所差异，在我国女性群体癌症发病率中，乳腺癌位居第一位[1]。目前临床治疗乳腺癌主要采用改良根治术和保乳手术（Breast-conserving surgery，BCS）联合辅助化疗治疗。前者能够彻底切除病灶，严重影响患者乳房外观;后者与单纯BCS相比术后复发率较低，且保留乳房减轻患者生理创伤与心理创伤，改善患者生活质量，临床可行性较高[2]。本研究62例乳腺癌患者采用保乳手术联合辅助化疗治疗，术后疗效值得肯定。现报道如下：

1  资料和方法

1.1 一般资料：采用随机数字表……