夏峰


【摘要】 目的:探讨晚期非小细胞肺癌患者的营养状况及影响因素。方法:选取2015年1月-2019年10月本院收治的晚期非小细胞肺癌患者208例。以全部患者最终的营养状况调查问卷得分中位数为截断值,将患者分为高分组和低分组,各104例。调查全部患者的营养状况,比较高分组和低分组的各项资料,通过单因素及多因素分析,探讨晚期非小细胞肺癌患者营养状况的影响因素。结果:全部患者的营养状况评分平均5.50(2.00,8.00)分;具有营养不良的患者比例为83.65%。患者的临床分期、BMI、KPS评分为晚期非小细胞肺癌患者营养状况的独立影响因素(P<0.05)。结论:晚期非小细胞肺癌患者大多存在营养不良的情况,部分因素构成晚期非小细胞肺癌患者营养状况的影响因素,在工作中可以进行具有针对性的干预。
【关键词】 非小细胞肺癌 营养状况 恶性肿瘤
Investigation of Nutritional Status and Influencing Factors in Patients with Advanced Non-small Cell Lung Cancer/XIA Feng. //Medical Innovation of China, 2021, 18(02): 0-060
[Abstract] Objective: To explore the nutritional status and influencing factors of patients with advanced non-small cell lung cancer. Method: A total of 208 patients with advanced non-small cell lung cancer admitted to our hospital from January 2015 to October 2019 were selected. Taking the median of the final nutritional status questionnaire scores of all patients as the truncated value, the patients were divided into the high score group and the low score group, 104 cases in each group. The nutritional status of all patients was investigated, the data of the high score group and low score group were compared, the influencing factors of nutritional status of patients with advanced non-small cell lung cancer were discussed through single-factor and multi-factor analysis. Result: The nutritional status score of all patients averaged 5.50 (2.00, 8.00) points, the proportion of patients with malnutrition was 83.65%. Clinical stage, BMI and KPS score were independent factors influencing the nutritional status of patients with advanced non-small cell lung cancer (P<0.05). Conclusion: Most patients with advanced non-small cell lung cancer have malnutrition, some factors constitute the influencing factors of the nutritional status of patients with advanced non-small cell lung cancer, targeted interventions can be carried out at work.
[Key words] Non-small cell lung cancer Nutritional status Malignant tumor
近些年在我國肺癌发病及死亡人数上升趋势十分明显,在恶性肿瘤中更是连续多年排名第一[1-2]。肺癌在早期缺乏典型的症状,进入中晚期后确诊及治疗已经失去最佳的治疗时机,预后不理想[3-5]。非小细胞肺癌在肺癌的患者之中的比例极高,其恶性程度高,病情进展迅速[6]。几乎所有的癌症患者在中晚期均会存在营养不良,体内能量以及营养物质的过度消耗又会对后续的治疗造成干扰而形成恶性循环,有调查结果显示,有1/5的癌症患者直接死亡原因就是营养不良[7-9]。本研究选择部分晚期非小细胞肺癌患者的病历资料进行分析,对该类患者的营养状况和影响因素进行分析,现报道如下。
1 资料与方法
1.1 一般资料 选取2015年1月-2019年10月本院收治的晚期非小细胞肺癌患者208例。(1)纳入标准:①以病理学诊断结果最终确诊为非小细胞肺癌,TNM分期为Ⅲ期或Ⅳ期;②入院前未使用专业的营养支持或营养摄入指导,首次诊断后接受治疗;③入院时年龄>18岁。(……