基于微信的随访干预模式对精神分裂症出院患者服药依从性的影响研究

周伟 余春燕 覃远珍 谭凤玲 彭述英 黎秀

[摘要]目的浅析基于微信的随访干预模式对精神分裂症出院患者服药依从性的影响研究。方法纳入广州市民政局精神病院于2019年5月至2020年2月收治的150例精神分裂症患者，采用随机数字表法将其分为观察组（ n=75）与对照组（ n=75），观察组给予基于微信的随访干预，对照组给予常规出院指导与定期电话随访，评价两组干预效果。结果观察组患者服药依从率为93.33%，高于对照组的76.00%，差异有统计学意义（ P <0.05）。两组干预前生活质量评分结果比较，差异无统计学意义（ P >0.05）;两组干预后生活质量评分高于干预前，且观察组干预后生活质量评分高于对照组，差异均有统计学意义（P <0.05）;观察组患者满意度为94.67%，高于对照组的73.33%，差异有统计学意义（ P <0.05）。结论精神分裂症出院患者应用基于微信的随访干预模式可提高患者服药依从率，改善生活质量，提高患者满意度。

[關键词]精神分裂症;随访;生活质量;满意度

[中图分类号] R473.74  [文献标识码] A   [文章编号]2095-0616（2021）23-0127-04

Research on the impacts of follow-up intervention model based on WeChat on medication compliance of discharged patients with schizophrenia

ZHOU  Wei1     YU  Chunyan1     QIN  Yuanzhen2     TAN  Fengling3     PENG 3Shuying    LI  Xiu1

1.Area III of Treatment， Mental Hospital of Bureau of Civil Affairs of Guangzhou Municipality， Guangdong， Guangzhou 510430， China;2.Day Rehabilitation Centre， Mental Hospital of Bureau of Civil Affairs of Guangzhou Municipality， Guangdong， Guangzhou 510430， China;3.Rehabilitation Clinic， Mental Hospital of Bureau of Civil Affairs of Guangzhou Municipality， Guangdong， Guangzhou 510430， China

[Abstract] Objective To analyze the impacts of follow-up intervention model based on WeChat on medication compliance of discharged patients with schizophrenia. Methods A total of 150 patients with schizophrenia admitted to Mental Hospital of Bureau of Civil Affairs of Guangzhou Municipality from May 2019 to February 2020 were selected and divided into the observation group （n=75） and the control group （n=75） according to the random number table method. The observation group was treated with follow-up intervention based on WeChat， while the control group was treated with conventional discharge guidance and regular telephone follow-up. And the intervention effects of the two groups were evaluated. Results The medication compliance rate of patients in the observation group was 93.33%， higher than 76.00% in the control group， with statistically significant difference（P <0.05）. There was no statistically significant difference in quality of life （QoL） score between the two groups before intervention （P >0.05）. The QoL scores of both groups after intervention were higher than those before intervention，and the QoL score of the observation group after intervention was higher than that of the control group，with statistically significant differences （P <0.05）. Patients' satisfaction in the observation group was 94.67%， higher than 73.33% in the control group， with statistically significant difference（P <0.05）. Conclusion The follow-up intervention model based on the application of WeChat can improve the medication compliance rate， QoL and satisfaction of discharged patients with schizophrenia.

[Key words] Schizophrenia; Follow up; Quality of life; Satisfaction

精神分裂症是常见的精神疾病，疾病特征包括个性改变、行为、情感、思维分裂表现、环境与精神活动不协调等，具有病程长、复发风险高、依从性差、疾病负担重、致残率高等特点，已经成为全世界范围内重要的公共卫生问题[1-2]。目前临床治疗方法以用药为主，但病程长，患者在长期治疗期间多存在服药依从性差以及药物不良反应等问题，患者出院后依从性普遍较差，可能形成自行停药、复发、再治疗、又停药的周期性波动情况，影响疾病预后效果，最终影响患者社会功能、日常生活，降低生活质量，因此精神分裂症患者院外康复阶段成为我国重要的医学与社会问题[3-4]。研究纳入广州市民政局精神病院于2019年5月至2020年2月收治的150例精神分裂症患者作研究对象，分析基于微信的随访干预效果，现报道如下。……