注射用哌拉西林钠舒巴坦钠在小儿肺炎临床疗效及不良反应的影响

陈玲 陈嵘峰

【摘要】目的：探讨注射用哌拉西林钠舒巴坦钠在小儿肺炎临床治疗中的效果与安全性分析。方法：选取我院2018年3月至2020年3月在我院治疗的54例肺炎患儿，根据住院先后顺序随机分为30例对照组和24例观察组。对照组用头孢替安治疗，观察组进行注射用哌拉西林钠舒巴坦钠治疗，对比分析两组患儿疗效及不良反应率德国情况。结果：治疗后观察组有效率（83.33%）高于对照组（56.67%），差异用统计学意义（P<0.05）；观察组患儿不良反应率（20.83%）低于对照组（46.67%），有统计学意义（P<0.05）。结论：注射用哌拉西林钠舒巴坦钠能提高小儿肺炎的治疗效果，不良反应少，药物更安全，适合推广。

【关键词】肺炎；哌拉西林舒巴坦钠；腹泻；皮疹；水肿

[中图分类号]R725.6 [文献标识码]A [文章编号]2096-5249（2021）05-0047-02

Effect of piperacillin sodium and Sulbactam Sodium for injection on clinical efficacy and adverse reactions of children with pneumonia

CHEN Ling， CHEN Rong-feng （Department of Pediatrics， BOLUO branch， Huizhou Central People’s Hospital， Huizhou Guangdong 516100， China）

[Abstract] Objective： To investigate the effect and safety of piperacillin sodium and Sulbactam Sodium for injection in the clinical treatment of children with pneumonia. Methods： 54 cases of pneumonia children in our hospital from March 2018 to March 2020 were selected and randomly divided into 30 cases of control group and 24 cases of observation group according to the sequence of hospitalization. The control group was treated with cefotiam， and the observation group was treated with piperacillin sodium and Sulbactam Sodium for injection. The efficacy and adverse reaction rate of the two groups were compared and analyzed. Results： after treatment， the effective rate of observation group （83.33%） was higher than that of control group （56.67%）， the difference was statistically significant （P<0.05）； the adverse reaction rate of observation group （20.83%） was lower than that of control group （46.67%）， with statistical significance （P<0.05）. Conclusion： piperacillin sodium and Sulbactam Sodium for injection can improve the treatment effect of pneumonia in children， with less adverse reactions and safer drug， which is suitable for promotion.

[Key words] pneumonia； piperacillin and sulbactam sodium； diarrhea； rash； edema

肺炎在小儿中常发，对肺、气管、支气管等造成影响，像痰液堵塞气道，咳喘不止等，患儿体感痛苦。如果反复发热，对患儿脑部也容易造成损伤，阻碍患儿发育。小儿肺炎发生后应尽快到院治疗，越快用药对患儿生命越有保障，臨床应重视小儿肺炎，在较短的时间内为患儿提供治疗，减轻患儿病痛。临床治疗对抗生素等药物应足够了解，保障药物在患儿体内的作用，降低药物的副作用，为患儿成长、发育做好保障。头孢替安是治疗小儿肺炎的有效药物，但容易残留在患儿体内，对机体造成一定影响[1]。注射用哌拉西林舒巴坦钠将哌拉西林与舒巴坦有效配比，药物针对肺炎，改变呼吸道感染情况，减少药物在机体中的副作用，提高药物安全性，患儿康复更有保障，详见下述。……