陈超
摘要:目的:探究普萘洛尔联合甲巯咪唑治疗甲亢的效果。方法:于2020年2月-2021年2月期间收治的70例甲亢患者为本次研究对象,应用简单数字表法将上述患者分为2组各35例。其中实验组给予普萘洛尔联合甲巯咪唑治疗;对照组仅应用甲巯咪唑治疗。对比分析2组甲状腺激素指标。结果:在甲状腺激素指标比较中,实验组低于对照组(P<0.05),差异有统计学意义。结论:在甲亢患者治疗中应用普萘洛尔联合甲巯咪唑治疗,可达到凸显的治疗效果,可改善甲状腺激素指标。该治疗方法可在临床上予以推广。
关键词:普萘洛尔;甲巯咪唑;甲亢
【Abstract】Objective: In this study, to explore the effect of propranolol combined with methimazole in the treatment of hyperthyroidism. Methods: 70 patients with hyperthyroidism admitted from February 2020 to February 2021 were the subjects of this study. The above patients were divided into 2 groups with 35 cases in each group using a simple digital table method. The experimental group was treated with propranolol combined with methimazole; the control group was only treated with methimazole. Comparative analysis of the two groups of thyroid hormone indicators. Results: In the comparison of thyroid hormone indicators, the experimental group was lower than the control group (P<0.05), and the difference was statistically significant. Conclusion: In this study, the application of propranolol combined with methimazole in the treatment of patients with hyperthyroidism can achieve prominent therapeutic effects and improve thyroid hormone indicators. This treatment method can be promoted clinically.
[Key words] propranolol; Methimazole; Hyperthyroidism
甲亢在臨床上较为多见,其是因机体内分泌系统障碍所致,本病体现为甲状腺肿大、心血管功能失衡以及神经系统功能失衡等症状,同时患者可出现多汗、消瘦以及易饿等[1]。目前,临床上多采取药物治疗以及手术治疗,由于手术治疗会产生创伤,且容易发生并发症,因此药物治疗就成为了最佳首选。本次研究中,在甲亢患者治疗中应用普萘洛尔联合甲巯咪唑治疗,探究其治疗效果。结果详见下文。
1 资料与方法
1.7 基础资料
于2020年2月-2021年2月期间收治的70例甲亢患者为本次研究对象,应用简单数字表法将上述患者分为2组各35例。基础资料:性别(实验组:男患21例,女患14例;对照组:男患20例,女患15例);年龄(实验组:19-58岁,平均年龄34.21±4.65岁;对照组:18-57岁,平均年龄34.65±4.65岁)。2组基础资料对比差异无统计学意义(P>0.05)。
1.8 方法
1.2.1对照组
对照组仅采取甲巯咪唑治疗,药物信息:上海黄海制药有限责任公司; 国药准字H31021243; 5mg.治疗方法:每日口服20mg,每日服用 3次,患者症状改善后将药物剂量更改为每次10mg,每天服用 1次。……