普伐他汀联合康复训练治疗脑梗死的临床效果

摘要：目的：探讨普伐他汀结合康复训练对脑梗死进行治疗的临床疗效及恢复期的疗效对比。方法：分別于2020年1年时间段择取确诊脑梗死患者纳80例，结合治疗差异不同将其分为除常规治疗（主要包括：奥扎格雷、疏血通以及阿司匹林）40例患者，此类患者为对照组，常规治疗联合普伐他汀结合康复训练治疗40例患者，此类患者为观察组，两组均治疗1周，比较两组患者经不同方式治疗前后临床改善情况（包括：NIHSS、Burke、ADL以及总有效率）。结果：治疗后1周，对照组与观察组对比，前者 NIHSS、Burke高于后者，前者ADL 评分与后者相比，前者显著偏高，两组差异较小，无可比性，（P<0.05）。前者总有效率与后者相比较，前者97.5%显著高于后者70.00%。结论：采用普伐他汀联合康复训练法对脑梗死患者有更好的临床效果且疗效更持久，不仅能恢复神经功能，还可以将日常生活能力恢复到较好状态，对于临床症状改善的得到有效提高，值得在临床中推广和应用。

关键词：普伐他汀;康复训练;脑梗死

[Abstract]： Objective： To explore the clinical efficacy of pravastatin combined with rehabilitation training in the treatment of cerebral infarction and the efficacy comparison in the convalescence period. Methods： In 2020， 80 patients with cerebral infarction were selected and divided into 40 patients except routine treatment （mainly including ozagrel， Shuxuetong and aspirin）. These patients were the control group， and 40 patients were treated with routine treatment combined with pravastatin and rehabilitation training. These patients were the observation group， and both groups were treated for 1 week. The clinical improvement before and after treatment in different ways was compared between the two groups （including NIHSS， NiHSS， NiHSS and NiHSS）. Results： One week after treatment， the NIHSS and Burke of the control group were higher than those of the observation group， while the ADL score of the former was significantly higher than that of the latter， with little difference and no comparability between the two groups （P<0.05）. Compared with the latter， the total effective rate of the former was 97.5%， which was significantly higher than that of the latter （70.00%）， and there was little difference between the two groups （P<0.05）. Conclusion： Pravastatin combined with rehabilitation training for patients with cerebral infarction has obvious clinical effect and longer lasting effect， is conducive to the recovery of neurological function and daily living ability， can improve the effective rate of clinical symptom improvement， and is worthy of clinical promotion and application.

[Key words]： pravastatin; Rehabilitation training; Cerebral infarction

【中图分类号】R4 【文献标识码】A 【文章编号】2107-2306（2021）14-02

脑梗死是一种脑血管疾病，在临床神经病学中最常见，主要发生在中老年。药物是调节心血管和脑血管疾病血液脂肪的首选药物。具有稳定斑块、抗炎等多方面作用，而普伐他汀由于其特殊的代谢方式，可以减少对肝脏功能的损害和药物中毒风险，适合中老年服用。长期以来，西医在临床上单纯对患者采用药物治疗，但治疗效果终是有限。根据相关资料，长期坚持进行科学、针对性训练的脑梗死患者反而实现了更好的恢复效果，失语、偏袒等临床症状都得到极大改善，间接提升了患者个人病后生活质量和家庭团结氛围。……