卡前列素氨丁三醇联合缩宫素在产后出血治疗中的应用效果分析

范娟

【摘 要】目的：探讨研究卡前列素氨丁三醇联合缩宫素在产后出血治疗中的应用效果。方法：选取我院2018年10月至2020年10月接收的产后出血患者80例，对照组利用缩宫素进行治疗，实验组采用卡前列素氨丁三醇联合缩宫素进行治疗，对两组患者的治疗有效率以及不良反应的发生情况进行对比分析。结果：对照组治疗有效率为80.0%（32/40），实验组治疗有效率为97.5%（39/40），差异具有一定的统计学意义（P<0.05）；对照组发生不良反应9例，不良反应发生率为22.5%，实验组发生不良反应2例，不良反应发生率为5.0%，差异具有一定的统计学意义（P<0.05）。结论：卡前列素氨丁三醇联合缩宫素在产后出血治疗中的应用效果明显优于单独利用缩宫素治疗，可以有效降低不良反应的发生率，值得临床上推广使用。

【关键词】卡前列素氨丁三醇；缩宫素；产后出血；不良反应

Analysis of the Application Effect of CarprostTromethamine Combined with Oxytocin in the Treatment of Postpartum Hemorrhage

FAN Juan

Maternal and child Health care family Planning Service Center of Tongcheng， Tongcheng， Anhui 231400， China

【Abstract】Objective：To study the application effect of carboprosttromethamine combined with oxytocin in the treatment of postpartum hemorrhage.Methods：Selected 80 patients with postpartum haemorrhage received by our hospital from October 2018 to October 2020， the control group was treated with oxytocin， and the experimental group was treated with carboprosttromethamine combined with oxytocin， and the treatment efficiency and the occurrence of adverse reactions between two groups were compared and analyzed. Results：The treatment effective rate of the control group was 80.0% （32/40）， and the treatment effective rate of the experimental group was 97.5% （39/40），the difference was statistically significant（P<0.05）；There were9 cases of adverse reactions occurred in the control group，the incidence of adverse reactions was 22.5%，in the experimental group， there were 2 cases of adverse reactions， and the incidence of adverse reactions was 5.0%，the difference was statistically significant（P<0.05）.Conclusion：The effect of carboprosttromethamine combined with oxytocin in the treatment of postpartum hemorrhage is significantly better than that of oxytocin alone， which can effectively reduce the incidence of adverse reactions and is worthy of clinical application.

【Key？Words】Carboprosttromethamine； Oxytocin； Postpartum hemorrhage；Adverse reactions

產后出血临床上指胎儿娩出后24h内产妇出血量超过500mL的疾病，产后出血是临床上导致孕产妇死亡的主要原因之一，引起产后出血的最常见原因为子宫收缩乏力[1]，研究显示约有70%的产后出血发生是由子宫收缩乏力导致。产后出血发病较急，对产妇的生命安全具有较为严重的影响。产后出血若治疗不当，采用的止血药物不当，只能用切除子宫等被动方式进行止血，对产妇的后期生活造成较为严重的影响。临床上对于产后出血的治疗通常采用增强子宫收缩能力的药物，常用的治疗方法为缩宫素治疗以及米索前列醇等，缩宫素属于一种肽类药物，其发挥作用与催产素相类似，可以有效抑制产后出血[2]。……