房间隔缺损封堵术与外科修补术对左室舒张功能远期影响观察研究

李颖 沈长琴 舒刚 李韬 王瑞华 朱文煜

【摘 要】目的：研究房間隔缺损封堵术与外科修补术对左室舒张功能远期影响。方法：从2018年9月至2020年9月在我院治疗房间隔缺损的患者中随机择取60例作为研究对象，按照数字表达法平均分成两组，每组30例患者。对照组接受外科修补术、观察组接受房间隔缺损封堵术。对比两组房间隔缺损患者手术指标和治疗6个月后的左室舒张功能。结果：治疗6个月后，观察组患者的E峰、A峰、E/A等指标改善情况明显优于对照组患者的相关指标改善情况，两组房间隔缺损患者的左室舒张功能数据差异有统计学意义（P<0.05）；观察组手术患者的术中出血量明显比对照组术中出血量少，手术时间、下床活动时间、住院时间明显比对照组所用时间短，两组房间隔缺损患者的手术指标差异有统计学意义（P<0.05）。结论：房间隔缺损患者接受房间隔缺损封堵术和外科修补术治疗后，症状均有所改善，其中房间隔缺损封堵术的作用效果更为显著，值得推广应用。

【关键词】左室舒张功能；房间隔缺损封堵术；外科修补术；远期疗效

Long-term effect of atrial septal defect closure and surgical repair on left ventricular diastolic function

LI Ying1， SHEN Changqin2， SHU Gang1， LI Tao1， WANG Ruihua1， ZHU Wenyu1 1.Department of Thoracic and Cardiac Surgery， Liupanshui People’s Hospital， Liupanshui，Guizhou 553001， China；2.Outpatient Department of Liupanshui People’s Hospital， Liupanshui，Guizhou 553001， China

【Abstract】Objective：To study the long-term effects of atrial septal defect closure and surgical repair on left ventricular diastolic function. Methods： A total of 60 patients with atrial septal defect treated in our hospital from September 2018 to September 2020 were randomly selec ted as research subjects and divided into two groups according to digital expression method， with 30 patients in each group. The control grou p received surgical repair and the observation group received atrial septal defect closure. The surgical indexes and left ventricular diastolic function of patients with atrial septal defect after 6 months of treatment were compared between the two groups.Results：After 6 months of tre atment， the improvement of E peak， A peak， E/A and other indicators in the observation group was significantly better than that in the contr ol group（P<0.05），there was significant difference in left ventricular diastolic function between the two groups（P<0.05）； The amount of intraoperative bleeding in the observation group was significantly less than that in the control group， and the operation time， out of bed activity time and hospitalization time were significantly shorter than those in the control group，there was significant difference in the operation indexes between the two groups（P<0.05）. Conclusion： The symptoms of patients with atrial septal defect were improved after the treatment of atria l septal defect occlusion and surgical repair， and the effect of atrial septal defect occlusion was more significant， which is worth popularizing.

【Key Words】Left ventricular diastolic function； Closure of atrial septal defect； Surgical repair； The long-term curative effect

房间隔缺损是先天性心脏疾病的一种，该疾病在发病早期并没有明顯的临床症状，但是心脏功能会受到一定的影响。近些年来，我国医疗技术在不断的发展进步，在房间隔缺损的治疗上取得了理想的成绩[1]。目前，治疗房间隔缺损最常用的两种方法为外科修补术和房间隔缺损封堵术，本次研究针对两种手术方法的远期疗效进行深入的分析。……