不同植骨材料应用于腰后路椎间植骨中的临床对比研究

李林峰　马文书　胡坤然

摘要：研究腰后路椎間植骨中应用不同植骨材料的临床效果。依据植骨材料分为自体髂骨块组、同种异体骨组，分析2组患者的植骨融合情况、螺钉位置不良、内固定失败情况、融合时间、手术时间、术中失血量、丢失高度、椎间高度、腰椎功能障碍程度、腰椎功能、生活质量、满意度。结果表明：自体髂骨块组患者的植骨融合率高于同种异体骨组（P<0.05），内固定失败率低于同种异体骨组（P<0.05）;自体髂骨块组患者的融合时间短于同种异体骨组（P<0.05），丢失高度少于同种异体骨组（P<0.05）。植骨后，自体髂骨块组患者的椎间高度、JOA评分均高于同种异体骨组（P<0.05），ODI评分低于同种异体骨组（P<0.05）;自体髂骨块组患者的疼痛与不适、对药物与医疗手段的依赖性评分均低于同种异体骨组（P<0.05），积极感受、总体健康、日常生活能力评分及平均总分均高于同种异体骨组（P<0.05）。自体髂骨块组患者的满意度88.00%高于同种异体骨组64.00%（P<0.05）。

关键词：腰后路椎间植骨;植骨材料;同种异体骨;字体髂骨块;植骨融合;腰椎功能

中图分类号：R687.3;R318.08

文献标识码：A文章编号：1001-5922（2022）06-0050-05

Clinical comparative study of different bone grafting materials used in lumbar posterior intervertebral bone grafting

LI Linfeng MA Wenshu HU Kunran

（1. The Second Department of Bone， the Second Affiliated Hospital of Xingtai Medical College，  Xingtai 054000， Hebei China;

2. Emergency Department of Xingtai General Hospital of North China Medical and Health Group， Xingtai 054000， Hebei China

）

Abstract：The paper studied the clinical effects of different bone graft materials in lumbar posterior intervertebral bone grafting. According to the bone graft materials， patients were divided into autogenous iliac bone block group and allograft group. The situation of bone graft fusion， poor screw position， internal fixation failure， fusion time， operation time， intraoperative blood loss， height of loss， intervertebral height， degree of lumbar dysfunction， lumbar function， quality of life and satisfaction of patients in the two groups were statistically analyzed. Results showed that the fusion rate of autogenous iliac bone was higher than that of allograft group （P<0.05）， and the failure rate of internal fixation was lower than that of allograft group （P<0.05）. The fusion time was shorter in the iliac autograft group than in the allograft group （P<0.05）， and the height of loss was shorter in the allograft group （P<0.05）. After bone grafting， intervertebral height and JOA score of patients in iliac autograft group were higher than those in allograft group （P<0.05）， while ODI score was lower than those in allograft group （P<0.05）. The scores of pain and discomfort， dependence on drugs and medical treatment in the iliac autograft group were lower than those in the allograft group （P<0.05）， and the scores of positive feeling， general health， daily living ability and average total score were higher than those in the allograft group （P<0.05）. The satisfaction rate of patients in iliac autograft group was 88.00% higher than that in allograft group 64.00% （P<0.05）.

Key words：lumbar posterior intervertebral bone graft; bone graft material; allogeneic bone; iliac bone block; bone graft fusion; lumbar function

在腰椎融合术中，目前后路腰椎椎间融合术是主流[1]。但现阶段，临床还没有统一植骨材料的选择。有相关医学统计数据显示[2]，各种材料有40%～100%的融合成功率。本研究统计分析了2019年2月至2021年12月月本院腰后路椎间植骨患者100例的临床资料，对比研究了腰后路椎间植骨中应用不同植骨材料的临床效果。

1资料与方法

1.1一般资料

选取2019年2月-2021年12月本院腰后路椎间植骨患者100例，依据植骨材料分为2组：自体髂骨块组和同种异体骨组。……